Quantifying Absolute Neutralization Titers against SARS-CoV-2 by a Standardized Virus Neutralization Assay Allows for Cross-Cohort Comparisons of COVID-19 Sera

Quantifying Absolute Neutralization Titers against SARS-CoV-2 by a Standardized Virus Neutralization Assay Allows for Cross-Cohort Comparisons of COVID-19 Sera

Vaccines and antibody-based therapeutics like convalescent-phase plasma therapy are premised upon inducing or transferring neutralizing antibodies that inhibit SARS-CoV-2 entry into cells. Virus neutralization assays (VNAs) for measuring neutralizing antibody titers (NATs) are an essential part of...

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Autores principales: Kasopefoluwa Y. Oguntuyo, Christian S. Stevens, Chuan Tien Hung, Satoshi Ikegame, Joshua A. Acklin, Shreyas S. Kowdle, Jillian C. Carmichael, Hsin-Ping Chiu, Kristopher D. Azarm, Griffin D. Haas, Fatima Amanat, Jéromine Klingler, Ian Baine, Suzanne Arinsburg, Juan C. Bandres, Mohammed N. A. Siddiquey, Robert M. Schilke, Matthew D. Woolard, Hongbo Zhang, Andrew J. Duty, Thomas A. Kraus, Thomas M. Moran, Domenico Tortorella, Jean K. Lim, Andrea V. Gamarnik, Catarina E. Hioe, Susan Zolla-Pazner, Stanimir S. Ivanov, Jeremy P. Kamil, Florian Krammer, Benhur Lee
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/9f425d57749f4d2aabcd8c8d41ea0f24
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spelling oai:doaj.org-article:9f425d57749f4d2aabcd8c8d41ea0f242021-11-03T18:15:38ZQuantifying Absolute Neutralization Titers against SARS-CoV-2 by a Standardized Virus Neutralization Assay Allows for Cross-Cohort Comparisons of COVID-19 Sera2161-21292150-751110.1128/mBio.02492-20https://doaj.org/article/9f425d57749f4d2aabcd8c8d41ea0f242021-02-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.02492-20https://doaj.org/toc/2161-2129https://doaj.org/toc/2150-7511 Vaccines and antibody-based therapeutics like convalescent-phase plasma therapy are premised upon inducing or transferring neutralizing antibodies that inhibit SARS-CoV-2 entry into cells. Virus neutralization assays (VNAs) for measuring neutralizing antibody titers (NATs) are an essential part of determining vaccine or therapeutic efficacy.Kasopefoluwa Y. OguntuyoChristian S. StevensChuan Tien HungSatoshi IkegameJoshua A. AcklinShreyas S. KowdleJillian C. CarmichaelHsin-Ping ChiuKristopher D. AzarmGriffin D. HaasFatima AmanatJéromine KlinglerIan BaineSuzanne ArinsburgJuan C. BandresMohammed N. A. SiddiqueyRobert M. SchilkeMatthew D. WoolardHongbo ZhangAndrew J. DutyThomas A. KrausThomas M. MoranDomenico TortorellaJean K. LimAndrea V. GamarnikCatarina E. HioeSusan Zolla-PaznerStanimir S. IvanovJeremy P. KamilFlorian KrammerBenhur LeeAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 1 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Kasopefoluwa Y. Oguntuyo
Christian S. Stevens
Chuan Tien Hung
Satoshi Ikegame
Joshua A. Acklin
Shreyas S. Kowdle
Jillian C. Carmichael
Hsin-Ping Chiu
Kristopher D. Azarm
Griffin D. Haas
Fatima Amanat
Jéromine Klingler
Ian Baine
Suzanne Arinsburg
Juan C. Bandres
Mohammed N. A. Siddiquey
Robert M. Schilke
Matthew D. Woolard
Hongbo Zhang
Andrew J. Duty
Thomas A. Kraus
Thomas M. Moran
Domenico Tortorella
Jean K. Lim
Andrea V. Gamarnik
Catarina E. Hioe
Susan Zolla-Pazner
Stanimir S. Ivanov
Jeremy P. Kamil
Florian Krammer
Benhur Lee
Quantifying Absolute Neutralization Titers against SARS-CoV-2 by a Standardized Virus Neutralization Assay Allows for Cross-Cohort Comparisons of COVID-19 Sera
description Vaccines and antibody-based therapeutics like convalescent-phase plasma therapy are premised upon inducing or transferring neutralizing antibodies that inhibit SARS-CoV-2 entry into cells. Virus neutralization assays (VNAs) for measuring neutralizing antibody titers (NATs) are an essential part of determining vaccine or therapeutic efficacy.
format article
author Kasopefoluwa Y. Oguntuyo
Christian S. Stevens
Chuan Tien Hung
Satoshi Ikegame
Joshua A. Acklin
Shreyas S. Kowdle
Jillian C. Carmichael
Hsin-Ping Chiu
Kristopher D. Azarm
Griffin D. Haas
Fatima Amanat
Jéromine Klingler
Ian Baine
Suzanne Arinsburg
Juan C. Bandres
Mohammed N. A. Siddiquey
Robert M. Schilke
Matthew D. Woolard
Hongbo Zhang
Andrew J. Duty
Thomas A. Kraus
Thomas M. Moran
Domenico Tortorella
Jean K. Lim
Andrea V. Gamarnik
Catarina E. Hioe
Susan Zolla-Pazner
Stanimir S. Ivanov
Jeremy P. Kamil
Florian Krammer
Benhur Lee
author_facet Kasopefoluwa Y. Oguntuyo
Christian S. Stevens
Chuan Tien Hung
Satoshi Ikegame
Joshua A. Acklin
Shreyas S. Kowdle
Jillian C. Carmichael
Hsin-Ping Chiu
Kristopher D. Azarm
Griffin D. Haas
Fatima Amanat
Jéromine Klingler
Ian Baine
Suzanne Arinsburg
Juan C. Bandres
Mohammed N. A. Siddiquey
Robert M. Schilke
Matthew D. Woolard
Hongbo Zhang
Andrew J. Duty
Thomas A. Kraus
Thomas M. Moran
Domenico Tortorella
Jean K. Lim
Andrea V. Gamarnik
Catarina E. Hioe
Susan Zolla-Pazner
Stanimir S. Ivanov
Jeremy P. Kamil
Florian Krammer
Benhur Lee
author_sort Kasopefoluwa Y. Oguntuyo
title Quantifying Absolute Neutralization Titers against SARS-CoV-2 by a Standardized Virus Neutralization Assay Allows for Cross-Cohort Comparisons of COVID-19 Sera
title_short Quantifying Absolute Neutralization Titers against SARS-CoV-2 by a Standardized Virus Neutralization Assay Allows for Cross-Cohort Comparisons of COVID-19 Sera
title_full Quantifying Absolute Neutralization Titers against SARS-CoV-2 by a Standardized Virus Neutralization Assay Allows for Cross-Cohort Comparisons of COVID-19 Sera
title_fullStr Quantifying Absolute Neutralization Titers against SARS-CoV-2 by a Standardized Virus Neutralization Assay Allows for Cross-Cohort Comparisons of COVID-19 Sera
title_full_unstemmed Quantifying Absolute Neutralization Titers against SARS-CoV-2 by a Standardized Virus Neutralization Assay Allows for Cross-Cohort Comparisons of COVID-19 Sera
title_sort quantifying absolute neutralization titers against sars-cov-2 by a standardized virus neutralization assay allows for cross-cohort comparisons of covid-19 sera
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/9f425d57749f4d2aabcd8c8d41ea0f24
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