The Host Cell Metabolite Inositol Hexakisphosphate Promotes Efficient Endogenous HIV-1 Reverse Transcription by Stabilizing the Viral Capsid
ABSTRACT A defining activity of retroviruses is reverse transcription, the process by which the viral genomic RNA is converted into the double-stranded DNA required for virus replication. Reverse transcriptase (RT), the viral enzyme responsible for this process, was identified in 1970 by assaying pe...
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Autores principales: | , , , , |
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Formato: | article |
Lenguaje: | EN |
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American Society for Microbiology
2020
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Acceso en línea: | https://doaj.org/article/9f4588bdb95c474798f388647168f867 |
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