Deciphering highly similar multigene family transcripts from Iso-Seq data with IsoCon

Transcripts from highly-similar multigene families are challenging to decipher. Here, the authors develop IsoCon, a tool for detecting and reconstructing isoforms from multigene families by analyzing long PacBio Iso-Seq reads.

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Autores principales: Kristoffer Sahlin, Marta Tomaszkiewicz, Kateryna D. Makova, Paul Medvedev
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/9f5d8d47200944ad99df5bbd232614b8
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spelling oai:doaj.org-article:9f5d8d47200944ad99df5bbd232614b82021-12-02T17:32:30ZDeciphering highly similar multigene family transcripts from Iso-Seq data with IsoCon10.1038/s41467-018-06910-x2041-1723https://doaj.org/article/9f5d8d47200944ad99df5bbd232614b82018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06910-xhttps://doaj.org/toc/2041-1723Transcripts from highly-similar multigene families are challenging to decipher. Here, the authors develop IsoCon, a tool for detecting and reconstructing isoforms from multigene families by analyzing long PacBio Iso-Seq reads.Kristoffer SahlinMarta TomaszkiewiczKateryna D. MakovaPaul MedvedevNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kristoffer Sahlin
Marta Tomaszkiewicz
Kateryna D. Makova
Paul Medvedev
Deciphering highly similar multigene family transcripts from Iso-Seq data with IsoCon
description Transcripts from highly-similar multigene families are challenging to decipher. Here, the authors develop IsoCon, a tool for detecting and reconstructing isoforms from multigene families by analyzing long PacBio Iso-Seq reads.
format article
author Kristoffer Sahlin
Marta Tomaszkiewicz
Kateryna D. Makova
Paul Medvedev
author_facet Kristoffer Sahlin
Marta Tomaszkiewicz
Kateryna D. Makova
Paul Medvedev
author_sort Kristoffer Sahlin
title Deciphering highly similar multigene family transcripts from Iso-Seq data with IsoCon
title_short Deciphering highly similar multigene family transcripts from Iso-Seq data with IsoCon
title_full Deciphering highly similar multigene family transcripts from Iso-Seq data with IsoCon
title_fullStr Deciphering highly similar multigene family transcripts from Iso-Seq data with IsoCon
title_full_unstemmed Deciphering highly similar multigene family transcripts from Iso-Seq data with IsoCon
title_sort deciphering highly similar multigene family transcripts from iso-seq data with isocon
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/9f5d8d47200944ad99df5bbd232614b8
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AT martatomaszkiewicz decipheringhighlysimilarmultigenefamilytranscriptsfromisoseqdatawithisocon
AT katerynadmakova decipheringhighlysimilarmultigenefamilytranscriptsfromisoseqdatawithisocon
AT paulmedvedev decipheringhighlysimilarmultigenefamilytranscriptsfromisoseqdatawithisocon
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