Virus-based vaccine vectors with distinct replication mechanisms differentially infect and activate dendritic cells

Abstract The precise mechanism by which many virus-based vectors activate immune responses remains unknown. Dendritic cells (DCs) play key roles in priming T cell responses and controlling virus replication, but their functions in generating protective immunity following vaccination with viral vecto...

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Autores principales: Carolina Chiale, Anthony M. Marchese, Yoichi Furuya, Michael D. Robek
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/9f635bc15de044ad91eccd5d62ec3467
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