Cryo-EM study of start codon selection during archaeal translation initiation

Initiation factor eIF2, common to eukaryotes and archaea, is a central actor in translation initiation. Here the authors describe two cryo-EM structures of archaeal 30S initiation complexes that provide a novel view of the central role that e/aIF2 plays in start codon selection.

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Autores principales:	Pierre-Damien Coureux, Christine Lazennec-Schurdevin, Auriane Monestier, Eric Larquet, Lionel Cladière, Bruno P. Klaholz, Emmanuelle Schmitt, Yves Mechulam
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9f668bacff76426980193744e1f8c4d1
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spelling	oai:doaj.org-article:9f668bacff76426980193744e1f8c4d12021-12-02T16:57:02ZCryo-EM study of start codon selection during archaeal translation initiation10.1038/ncomms133662041-1723https://doaj.org/article/9f668bacff76426980193744e1f8c4d12016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13366https://doaj.org/toc/2041-1723Initiation factor eIF2, common to eukaryotes and archaea, is a central actor in translation initiation. Here the authors describe two cryo-EM structures of archaeal 30S initiation complexes that provide a novel view of the central role that e/aIF2 plays in start codon selection.Pierre-Damien CoureuxChristine Lazennec-SchurdevinAuriane MonestierEric LarquetLionel CladièreBruno P. KlaholzEmmanuelle SchmittYves MechulamNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Pierre-Damien Coureux Christine Lazennec-Schurdevin Auriane Monestier Eric Larquet Lionel Cladière Bruno P. Klaholz Emmanuelle Schmitt Yves Mechulam Cryo-EM study of start codon selection during archaeal translation initiation
description	Initiation factor eIF2, common to eukaryotes and archaea, is a central actor in translation initiation. Here the authors describe two cryo-EM structures of archaeal 30S initiation complexes that provide a novel view of the central role that e/aIF2 plays in start codon selection.
format	article
author	Pierre-Damien Coureux Christine Lazennec-Schurdevin Auriane Monestier Eric Larquet Lionel Cladière Bruno P. Klaholz Emmanuelle Schmitt Yves Mechulam
author_facet	Pierre-Damien Coureux Christine Lazennec-Schurdevin Auriane Monestier Eric Larquet Lionel Cladière Bruno P. Klaholz Emmanuelle Schmitt Yves Mechulam
author_sort	Pierre-Damien Coureux
title	Cryo-EM study of start codon selection during archaeal translation initiation
title_short	Cryo-EM study of start codon selection during archaeal translation initiation
title_full	Cryo-EM study of start codon selection during archaeal translation initiation
title_fullStr	Cryo-EM study of start codon selection during archaeal translation initiation
title_full_unstemmed	Cryo-EM study of start codon selection during archaeal translation initiation
title_sort	cryo-em study of start codon selection during archaeal translation initiation
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/9f668bacff76426980193744e1f8c4d1
work_keys_str_mv	AT pierredamiencoureux cryoemstudyofstartcodonselectionduringarchaealtranslationinitiation AT christinelazennecschurdevin cryoemstudyofstartcodonselectionduringarchaealtranslationinitiation AT aurianemonestier cryoemstudyofstartcodonselectionduringarchaealtranslationinitiation AT ericlarquet cryoemstudyofstartcodonselectionduringarchaealtranslationinitiation AT lionelcladiere cryoemstudyofstartcodonselectionduringarchaealtranslationinitiation AT brunopklaholz cryoemstudyofstartcodonselectionduringarchaealtranslationinitiation AT emmanuelleschmitt cryoemstudyofstartcodonselectionduringarchaealtranslationinitiation AT yvesmechulam cryoemstudyofstartcodonselectionduringarchaealtranslationinitiation
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Cryo-EM study of start codon selection during archaeal translation initiation

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