Activating an anterior nucleus gigantocellularis subpopulation triggers emergence from pharmacologically-induced coma in rodents

The reticular activating system (RAS) of the brainstem regulates wakefulness, and stimulation of RAS areas can reverse effects of anaesthesia. Here, the authors show that stimulation of a particular RAS area, the anterior portion of nucleus gigantocellularis, can produce arousal from deep coma.

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Autores principales:	S. Gao, A. Proekt, N. Renier, D. P. Calderon, D. W. Pfaff
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9f743d8f239245c0a4937e673cd9d525
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spelling	oai:doaj.org-article:9f743d8f239245c0a4937e673cd9d5252021-12-02T17:31:37ZActivating an anterior nucleus gigantocellularis subpopulation triggers emergence from pharmacologically-induced coma in rodents10.1038/s41467-019-10797-72041-1723https://doaj.org/article/9f743d8f239245c0a4937e673cd9d5252019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10797-7https://doaj.org/toc/2041-1723The reticular activating system (RAS) of the brainstem regulates wakefulness, and stimulation of RAS areas can reverse effects of anaesthesia. Here, the authors show that stimulation of a particular RAS area, the anterior portion of nucleus gigantocellularis, can produce arousal from deep coma.S. GaoA. ProektN. RenierD. P. CalderonD. W. PfaffNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q S. Gao A. Proekt N. Renier D. P. Calderon D. W. Pfaff Activating an anterior nucleus gigantocellularis subpopulation triggers emergence from pharmacologically-induced coma in rodents
description	The reticular activating system (RAS) of the brainstem regulates wakefulness, and stimulation of RAS areas can reverse effects of anaesthesia. Here, the authors show that stimulation of a particular RAS area, the anterior portion of nucleus gigantocellularis, can produce arousal from deep coma.
format	article
author	S. Gao A. Proekt N. Renier D. P. Calderon D. W. Pfaff
author_facet	S. Gao A. Proekt N. Renier D. P. Calderon D. W. Pfaff
author_sort	S. Gao
title	Activating an anterior nucleus gigantocellularis subpopulation triggers emergence from pharmacologically-induced coma in rodents
title_short	Activating an anterior nucleus gigantocellularis subpopulation triggers emergence from pharmacologically-induced coma in rodents
title_full	Activating an anterior nucleus gigantocellularis subpopulation triggers emergence from pharmacologically-induced coma in rodents
title_fullStr	Activating an anterior nucleus gigantocellularis subpopulation triggers emergence from pharmacologically-induced coma in rodents
title_full_unstemmed	Activating an anterior nucleus gigantocellularis subpopulation triggers emergence from pharmacologically-induced coma in rodents
title_sort	activating an anterior nucleus gigantocellularis subpopulation triggers emergence from pharmacologically-induced coma in rodents
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/9f743d8f239245c0a4937e673cd9d525
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Activating an anterior nucleus gigantocellularis subpopulation triggers emergence from pharmacologically-induced coma in rodents

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