PHARMACOECONOMICS OF APPLICATION OF HEPATOPROTECTORS IN THERAPY OF DRUG-INDUCED LIVER INJURY AFTER CHEMOTHERAPY

One of the major problems of modern oncology drug is liver damage, requiring additional costs for its treatment. The aim of our work was to study medical and economic efficiency of various schemes of hepatoprotective treatment of toxic liver damage. The paper presents the use of pharmacoeconomic stu...

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Autores principales:	D. D. Morikov, E. G. Morikova, D. M. Ponomarenko
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2017
Materias:	pharmacoeconomics direct costs efficiency Science Q
Acceso en línea:	https://doaj.org/article/9f74bdacb3ba414ebdd8ebda0aef5af3
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spelling	oai:doaj.org-article:9f74bdacb3ba414ebdd8ebda0aef5af32021-11-23T06:14:37ZPHARMACOECONOMICS OF APPLICATION OF HEPATOPROTECTORS IN THERAPY OF DRUG-INDUCED LIVER INJURY AFTER CHEMOTHERAPY2541-94202587-959610.12737/article_59a614fb8002d5.90108157https://doaj.org/article/9f74bdacb3ba414ebdd8ebda0aef5af32017-04-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/619https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596One of the major problems of modern oncology drug is liver damage, requiring additional costs for its treatment. The aim of our work was to study medical and economic efficiency of various schemes of hepatoprotective treatment of toxic liver damage. The paper presents the use of pharmacoeconomic studies in the treatment of hepatic drug-induced hepatitis, which occurs after chemotherapy in patients with Hodgkin's lymphoma. The study was conducted in the two comparison groups on a "cost - effectiveness". This method was chosen because it is in effect depending on the process (method), treatment was varied, as well as costs incurred. The unit of the effect of the number of days required for the relief of hepatic failure has been selected. Economic analysis of the work includes not only toxic hepatitis therapy, and treatment of any disease complications such as hepatic encephalopathy. The study revealed that the effectiveness of therapy increased 1.4 times and the economic costs were 51.8 % reduced with hepatoprotective drug "remaxol".D. D. MorikovE. G. MorikovaD. M. PonomarenkoScientific Сentre for Family Health and Human Reproduction Problemsarticlepharmacoeconomicsdirect costsefficiencyScienceQRUActa Biomedica Scientifica, Vol 2, Iss 2, Pp 54-58 (2017)
institution	DOAJ
collection	DOAJ
language	RU
topic	pharmacoeconomics direct costs efficiency Science Q
spellingShingle	pharmacoeconomics direct costs efficiency Science Q D. D. Morikov E. G. Morikova D. M. Ponomarenko PHARMACOECONOMICS OF APPLICATION OF HEPATOPROTECTORS IN THERAPY OF DRUG-INDUCED LIVER INJURY AFTER CHEMOTHERAPY
description	One of the major problems of modern oncology drug is liver damage, requiring additional costs for its treatment. The aim of our work was to study medical and economic efficiency of various schemes of hepatoprotective treatment of toxic liver damage. The paper presents the use of pharmacoeconomic studies in the treatment of hepatic drug-induced hepatitis, which occurs after chemotherapy in patients with Hodgkin's lymphoma. The study was conducted in the two comparison groups on a "cost - effectiveness". This method was chosen because it is in effect depending on the process (method), treatment was varied, as well as costs incurred. The unit of the effect of the number of days required for the relief of hepatic failure has been selected. Economic analysis of the work includes not only toxic hepatitis therapy, and treatment of any disease complications such as hepatic encephalopathy. The study revealed that the effectiveness of therapy increased 1.4 times and the economic costs were 51.8 % reduced with hepatoprotective drug "remaxol".
format	article
author	D. D. Morikov E. G. Morikova D. M. Ponomarenko
author_facet	D. D. Morikov E. G. Morikova D. M. Ponomarenko
author_sort	D. D. Morikov
title	PHARMACOECONOMICS OF APPLICATION OF HEPATOPROTECTORS IN THERAPY OF DRUG-INDUCED LIVER INJURY AFTER CHEMOTHERAPY
title_short	PHARMACOECONOMICS OF APPLICATION OF HEPATOPROTECTORS IN THERAPY OF DRUG-INDUCED LIVER INJURY AFTER CHEMOTHERAPY
title_full	PHARMACOECONOMICS OF APPLICATION OF HEPATOPROTECTORS IN THERAPY OF DRUG-INDUCED LIVER INJURY AFTER CHEMOTHERAPY
title_fullStr	PHARMACOECONOMICS OF APPLICATION OF HEPATOPROTECTORS IN THERAPY OF DRUG-INDUCED LIVER INJURY AFTER CHEMOTHERAPY
title_full_unstemmed	PHARMACOECONOMICS OF APPLICATION OF HEPATOPROTECTORS IN THERAPY OF DRUG-INDUCED LIVER INJURY AFTER CHEMOTHERAPY
title_sort	pharmacoeconomics of application of hepatoprotectors in therapy of drug-induced liver injury after chemotherapy
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2017
url	https://doaj.org/article/9f74bdacb3ba414ebdd8ebda0aef5af3
work_keys_str_mv	AT ddmorikov pharmacoeconomicsofapplicationofhepatoprotectorsintherapyofdruginducedliverinjuryafterchemotherapy AT egmorikova pharmacoeconomicsofapplicationofhepatoprotectorsintherapyofdruginducedliverinjuryafterchemotherapy AT dmponomarenko pharmacoeconomicsofapplicationofhepatoprotectorsintherapyofdruginducedliverinjuryafterchemotherapy
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PHARMACOECONOMICS OF APPLICATION OF HEPATOPROTECTORS IN THERAPY OF DRUG-INDUCED LIVER INJURY AFTER CHEMOTHERAPY

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