Hormone secreting juvenile granulosa cell tumor of the ovary in an infant presenting with massive ascites and precocious pseudopuberty

Juvenile granulosa cell tumors (JGCTs), account for 4–5% of GCTs, the rare sex cord stromal tumors. Presentation of JGCTs in infants is even rarer. We present case of a 3-month-old female infant with abdominal distension, feeding intolerance and fever of 10 days' duration. The child had gross a...

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Autores principales:	Minakshi Bhosale, Jyoti Kudrimoti, Deepak Dangmali
Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer Medknow Publications 2021
Materias:	infant inhibin juvenile granulosa cell tumor ovary precocious pseudopuberty Medicine R Nursing RT1-120
Acceso en línea:	https://doaj.org/article/9f7b1fc2f5674bc2a2e78a7287ea3bbb
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spelling	oai:doaj.org-article:9f7b1fc2f5674bc2a2e78a7287ea3bbb2021-11-12T10:09:48ZHormone secreting juvenile granulosa cell tumor of the ovary in an infant presenting with massive ascites and precocious pseudopuberty2348-33342348-506X10.4103/cjhr.cjhr_39_20https://doaj.org/article/9f7b1fc2f5674bc2a2e78a7287ea3bbb2021-01-01T00:00:00Zhttp://www.cjhr.org/article.asp?issn=2348-3334;year=2021;volume=8;issue=2;spage=136;epage=138;aulast=Bhosalehttps://doaj.org/toc/2348-3334https://doaj.org/toc/2348-506XJuvenile granulosa cell tumors (JGCTs), account for 4–5% of GCTs, the rare sex cord stromal tumors. Presentation of JGCTs in infants is even rarer. We present case of a 3-month-old female infant with abdominal distension, feeding intolerance and fever of 10 days' duration. The child had gross abdominal distension causing visible respiratory distress. She also had signs of isosexual precocious puberty. Radiological evaluation was suggestive of left ovarian tumor. Left oophorectomy with preservation of the fallopian tube was done after hemodynamic stabilization. Histopathology evaluation of the tumor was suggestive of JGCT, which was confirmed on immunohistochemical evaluation. On 1 year follow-up, the child is stable, has achieved age-appropriate milestones and is tumor-free. Parents have been explained importance of regular follow-up to detect tumor recurrence. This is probably the youngest case of JGCT presenting with precocious puberty reported in literature so far.Minakshi BhosaleJyoti KudrimotiDeepak DangmaliWolters Kluwer Medknow Publicationsarticle infantinhibinjuvenile granulosa cell tumorovaryprecocious pseudopuberty MedicineRNursingRT1-120ENCHRISMED Journal of Health and Research, Vol 8, Iss 2, Pp 136-138 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	infant inhibin juvenile granulosa cell tumor ovary precocious pseudopuberty Medicine R Nursing RT1-120
spellingShingle	infant inhibin juvenile granulosa cell tumor ovary precocious pseudopuberty Medicine R Nursing RT1-120 Minakshi Bhosale Jyoti Kudrimoti Deepak Dangmali Hormone secreting juvenile granulosa cell tumor of the ovary in an infant presenting with massive ascites and precocious pseudopuberty
description	Juvenile granulosa cell tumors (JGCTs), account for 4–5% of GCTs, the rare sex cord stromal tumors. Presentation of JGCTs in infants is even rarer. We present case of a 3-month-old female infant with abdominal distension, feeding intolerance and fever of 10 days' duration. The child had gross abdominal distension causing visible respiratory distress. She also had signs of isosexual precocious puberty. Radiological evaluation was suggestive of left ovarian tumor. Left oophorectomy with preservation of the fallopian tube was done after hemodynamic stabilization. Histopathology evaluation of the tumor was suggestive of JGCT, which was confirmed on immunohistochemical evaluation. On 1 year follow-up, the child is stable, has achieved age-appropriate milestones and is tumor-free. Parents have been explained importance of regular follow-up to detect tumor recurrence. This is probably the youngest case of JGCT presenting with precocious puberty reported in literature so far.
format	article
author	Minakshi Bhosale Jyoti Kudrimoti Deepak Dangmali
author_facet	Minakshi Bhosale Jyoti Kudrimoti Deepak Dangmali
author_sort	Minakshi Bhosale
title	Hormone secreting juvenile granulosa cell tumor of the ovary in an infant presenting with massive ascites and precocious pseudopuberty
title_short	Hormone secreting juvenile granulosa cell tumor of the ovary in an infant presenting with massive ascites and precocious pseudopuberty
title_full	Hormone secreting juvenile granulosa cell tumor of the ovary in an infant presenting with massive ascites and precocious pseudopuberty
title_fullStr	Hormone secreting juvenile granulosa cell tumor of the ovary in an infant presenting with massive ascites and precocious pseudopuberty
title_full_unstemmed	Hormone secreting juvenile granulosa cell tumor of the ovary in an infant presenting with massive ascites and precocious pseudopuberty
title_sort	hormone secreting juvenile granulosa cell tumor of the ovary in an infant presenting with massive ascites and precocious pseudopuberty
publisher	Wolters Kluwer Medknow Publications
publishDate	2021
url	https://doaj.org/article/9f7b1fc2f5674bc2a2e78a7287ea3bbb
work_keys_str_mv	AT minakshibhosale hormonesecretingjuvenilegranulosacelltumoroftheovaryinaninfantpresentingwithmassiveascitesandprecociouspseudopuberty AT jyotikudrimoti hormonesecretingjuvenilegranulosacelltumoroftheovaryinaninfantpresentingwithmassiveascitesandprecociouspseudopuberty AT deepakdangmali hormonesecretingjuvenilegranulosacelltumoroftheovaryinaninfantpresentingwithmassiveascitesandprecociouspseudopuberty
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Hormone secreting juvenile granulosa cell tumor of the ovary in an infant presenting with massive ascites and precocious pseudopuberty

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