Azilsartan Suppresses Osteoclastogenesis and Ameliorates Ovariectomy-Induced Osteoporosis by Inhibiting Reactive Oxygen Species Production and Activating Nrf2 Signaling

Osteoporosis is characterized by a decrease in bone mass and destruction of the bone microarchitecture, and it commonly occurs in postmenopausal women and the elderly. Overactivation of osteoclasts caused by the inflammatory response or oxidative stress leads to osteoporosis. An increasing number of...

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Bibliographic Details
Main Authors: Bin Pan, Lin Zheng, Jiawei Fang, Ye Lin, Hehuan Lai, Jiawei Gao, Wenzheng Pan, Yejin Zhang, Kainan Ni, Chao Lou, Dengwei He
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
Online Access:https://doaj.org/article/9f7d8149ba67406f8401abd0d475ae73
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