Impact of heat treatment on size, structure, and bioactivity of elemental selenium nanoparticles

Jinsong Zhang1, Ethan W Taylor2, Xiaochun Wan1, Dungeng Peng31School of Tea and Food Science, Anhui Agricultural University, Anhui, People&#39;s Republic of China; 2Department of Nanoscience, Joint School of Nanoscience and Nanoengineering, University of North Carolina at Greensboro, Greensb...

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Autores principales:	Wan X, Taylor EW, Zhang J, Peng D
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/9f84ab8a674b41349d5c154238bb9ee7
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spelling	oai:doaj.org-article:9f84ab8a674b41349d5c154238bb9ee72021-12-02T01:50:41ZImpact of heat treatment on size, structure, and bioactivity of elemental selenium nanoparticles1176-91141178-2013https://doaj.org/article/9f84ab8a674b41349d5c154238bb9ee72012-02-01T00:00:00Zhttp://www.dovepress.com/impact-of-heat-treatment-on-size-structure-and-bioactivity-of-elementa-a9292https://doaj.org/toc/1176-9114https://doaj.org/toc/1178-2013Jinsong Zhang1, Ethan W Taylor2, Xiaochun Wan1, Dungeng Peng31School of Tea and Food Science, Anhui Agricultural University, Anhui, People&#39;s Republic of China; 2Department of Nanoscience, Joint School of Nanoscience and Nanoengineering, University of North Carolina at Greensboro, Greensboro, NC, 3Department of Biochemistry, Vanderbilt University, Nashville, TN, USABackground: Elemental selenium nanoparticles have emerged as a novel selenium source with the advantage of reduced risk of selenium toxicity. The present work investigated whether heat treatment affects the size, structure, and bioactivity of selenium nanoparticles.Methods and results: After a one-hour incubation of solution containing 80 nm selenium particles in a 90&deg;C water bath, the nanoparticles aggregated into larger 110 nm particles and nanorods (290 nm &times; 70 nm), leading to significantly reduced bioavailability and phase II enzyme induction in selenium-deficient mice. When a solution containing 40 nm selenium nanoparticles was treated under the same conditions, the nanoparticles aggregated into larger 72 nm particles but did not transform into nanorods, demonstrating that the thermostability of selenium nanoparticles is size-dependent, smaller selenium nanoparticles being more resistant than larger selenium nanoparticles to transformation into nanorods during heat treatment.Conclusion: The present results suggest that temperature and duration of the heat process, as well as the original nanoparticle size, should be carefully selected when a solution containing selenium nanoparticles is added to functional foods.Keywords: nanoparticle, selenium, bioactivity, heat treatmentWan XTaylor EWZhang JPeng DDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2012, Iss default, Pp 815-825 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Wan X Taylor EW Zhang J Peng D Impact of heat treatment on size, structure, and bioactivity of elemental selenium nanoparticles
description	Jinsong Zhang1, Ethan W Taylor2, Xiaochun Wan1, Dungeng Peng31School of Tea and Food Science, Anhui Agricultural University, Anhui, People&#39;s Republic of China; 2Department of Nanoscience, Joint School of Nanoscience and Nanoengineering, University of North Carolina at Greensboro, Greensboro, NC, 3Department of Biochemistry, Vanderbilt University, Nashville, TN, USABackground: Elemental selenium nanoparticles have emerged as a novel selenium source with the advantage of reduced risk of selenium toxicity. The present work investigated whether heat treatment affects the size, structure, and bioactivity of selenium nanoparticles.Methods and results: After a one-hour incubation of solution containing 80 nm selenium particles in a 90&deg;C water bath, the nanoparticles aggregated into larger 110 nm particles and nanorods (290 nm &times; 70 nm), leading to significantly reduced bioavailability and phase II enzyme induction in selenium-deficient mice. When a solution containing 40 nm selenium nanoparticles was treated under the same conditions, the nanoparticles aggregated into larger 72 nm particles but did not transform into nanorods, demonstrating that the thermostability of selenium nanoparticles is size-dependent, smaller selenium nanoparticles being more resistant than larger selenium nanoparticles to transformation into nanorods during heat treatment.Conclusion: The present results suggest that temperature and duration of the heat process, as well as the original nanoparticle size, should be carefully selected when a solution containing selenium nanoparticles is added to functional foods.Keywords: nanoparticle, selenium, bioactivity, heat treatment
format	article
author	Wan X Taylor EW Zhang J Peng D
author_facet	Wan X Taylor EW Zhang J Peng D
author_sort	Wan X
title	Impact of heat treatment on size, structure, and bioactivity of elemental selenium nanoparticles
title_short	Impact of heat treatment on size, structure, and bioactivity of elemental selenium nanoparticles
title_full	Impact of heat treatment on size, structure, and bioactivity of elemental selenium nanoparticles
title_fullStr	Impact of heat treatment on size, structure, and bioactivity of elemental selenium nanoparticles
title_full_unstemmed	Impact of heat treatment on size, structure, and bioactivity of elemental selenium nanoparticles
title_sort	impact of heat treatment on size, structure, and bioactivity of elemental selenium nanoparticles
publisher	Dove Medical Press
publishDate	2012
url	https://doaj.org/article/9f84ab8a674b41349d5c154238bb9ee7
work_keys_str_mv	AT wanx impactofheattreatmentonsizestructureandbioactivityofelementalseleniumnanoparticles AT taylorew impactofheattreatmentonsizestructureandbioactivityofelementalseleniumnanoparticles AT zhangj impactofheattreatmentonsizestructureandbioactivityofelementalseleniumnanoparticles AT pengd impactofheattreatmentonsizestructureandbioactivityofelementalseleniumnanoparticles
_version_	1718402858306502656

Impact of heat treatment on size, structure, and bioactivity of elemental selenium nanoparticles

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