Comparison between the EX-PRESS P-50 implant and trabeculectomy in patients with open-angle glaucoma

María Elena Mendoza-Mendieta,1 Ana Paola López-Venegas,2 Gerardo Valdés-Casas3 1Department of Anterior Segment, Dr Luis Sánchez Bulnes Hospital, Association to Prevent Blindness, Mexico City, Mexico; 2Institute of Ophthalmology, Conde de Valenciana, Mexic...

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Autores principales:	Mendoza-Mendieta ME, López-Venegas AP, Valdés-Casas G
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	glaucoma IOP EX-PRESS Trabeculectomy. Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/9f861331c13842e58727a993034ca767
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spelling	oai:doaj.org-article:9f861331c13842e58727a993034ca7672021-12-02T01:18:01ZComparison between the EX-PRESS P-50 implant and trabeculectomy in patients with open-angle glaucoma1177-5483https://doaj.org/article/9f861331c13842e58727a993034ca7672016-02-01T00:00:00Zhttps://www.dovepress.com/comparison-between-the-ex-press-p-50-implant-and-trabeculectomy-in-pat-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483María Elena Mendoza-Mendieta,1 Ana Paola López-Venegas,2 Gerardo Valdés-Casas3 1Department of Anterior Segment, Dr Luis Sánchez Bulnes Hospital, Association to Prevent Blindness, Mexico City, Mexico; 2Institute of Ophthalmology, Conde de Valenciana, Mexico City, Mexico; 3Department of General Ophthalmology, Institute of Ophthalmology, Conde de Valenciana, Mexico City, Mexico Purpose: To evaluate the EX-PRESS P-50 implant compared to standard trabeculectomy (TBC). Methods: Single-center prospective randomized study; 20 eyes of 20 patients were treated with the EX-PRESS P-50 implant, and 20 eyes of 20 patients with TBC, over a 19-month period. Records of all patients were reviewed and compared. Success was defined as intraocular pressure (IOP) <21 and >5 mmHg or a decrease of 30% of IOP. Failure was defined as >21 mmHg or decline in visual acuity. Statistical analysis was made with Student’s t-test and χ2 test analyzed with SPSS version 13.0. Results: The average follow-up was 8.6 months (±4.9 months) for the EX-PRESS P-50 group and 9.6 months (±5.3 months) for the TBC group. The postoperative visual acuity and IOP were not significantly different. We report more complications in the EX-PRESS P-50 group. At 3, 6, and 12 months follow-up, the control group was found to be free of complications, whereas multiple complications were observed in the EX-PRESS P-50 group at 3 and 6 months follow-up. We found no differences in either group with respect to success. Conclusion: Both procedures are equally effective for the treatment of glaucoma, with 80% success in the EX-PRESS P-50 group and 72.7% in the control group. Keywords: glaucoma, IOP, EX-PRESS, trabeculectomyMendoza-Mendieta MELópez-Venegas APValdés-Casas GDove Medical PressarticleglaucomaIOPEX-PRESSTrabeculectomy.OphthalmologyRE1-994ENClinical Ophthalmology, Vol 2016, Iss Issue 1, Pp 269-276 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	glaucoma IOP EX-PRESS Trabeculectomy. Ophthalmology RE1-994
spellingShingle	glaucoma IOP EX-PRESS Trabeculectomy. Ophthalmology RE1-994 Mendoza-Mendieta ME López-Venegas AP Valdés-Casas G Comparison between the EX-PRESS P-50 implant and trabeculectomy in patients with open-angle glaucoma
description	María Elena Mendoza-Mendieta,1 Ana Paola López-Venegas,2 Gerardo Valdés-Casas3 1Department of Anterior Segment, Dr Luis Sánchez Bulnes Hospital, Association to Prevent Blindness, Mexico City, Mexico; 2Institute of Ophthalmology, Conde de Valenciana, Mexico City, Mexico; 3Department of General Ophthalmology, Institute of Ophthalmology, Conde de Valenciana, Mexico City, Mexico Purpose: To evaluate the EX-PRESS P-50 implant compared to standard trabeculectomy (TBC). Methods: Single-center prospective randomized study; 20 eyes of 20 patients were treated with the EX-PRESS P-50 implant, and 20 eyes of 20 patients with TBC, over a 19-month period. Records of all patients were reviewed and compared. Success was defined as intraocular pressure (IOP) <21 and >5 mmHg or a decrease of 30% of IOP. Failure was defined as >21 mmHg or decline in visual acuity. Statistical analysis was made with Student’s t-test and χ2 test analyzed with SPSS version 13.0. Results: The average follow-up was 8.6 months (±4.9 months) for the EX-PRESS P-50 group and 9.6 months (±5.3 months) for the TBC group. The postoperative visual acuity and IOP were not significantly different. We report more complications in the EX-PRESS P-50 group. At 3, 6, and 12 months follow-up, the control group was found to be free of complications, whereas multiple complications were observed in the EX-PRESS P-50 group at 3 and 6 months follow-up. We found no differences in either group with respect to success. Conclusion: Both procedures are equally effective for the treatment of glaucoma, with 80% success in the EX-PRESS P-50 group and 72.7% in the control group. Keywords: glaucoma, IOP, EX-PRESS, trabeculectomy
format	article
author	Mendoza-Mendieta ME López-Venegas AP Valdés-Casas G
author_facet	Mendoza-Mendieta ME López-Venegas AP Valdés-Casas G
author_sort	Mendoza-Mendieta ME
title	Comparison between the EX-PRESS P-50 implant and trabeculectomy in patients with open-angle glaucoma
title_short	Comparison between the EX-PRESS P-50 implant and trabeculectomy in patients with open-angle glaucoma
title_full	Comparison between the EX-PRESS P-50 implant and trabeculectomy in patients with open-angle glaucoma
title_fullStr	Comparison between the EX-PRESS P-50 implant and trabeculectomy in patients with open-angle glaucoma
title_full_unstemmed	Comparison between the EX-PRESS P-50 implant and trabeculectomy in patients with open-angle glaucoma
title_sort	comparison between the ex-press p-50 implant and trabeculectomy in patients with open-angle glaucoma
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/9f861331c13842e58727a993034ca767
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Comparison between the EX-PRESS P-50 implant and trabeculectomy in patients with open-angle glaucoma

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