A reference haplotype panel for genome-wide imputation of short tandem repeats

Short-tandem repeats (STR), similar to single nucleotide polymorphisms (SNP), contribute to complex traits, but their ascertainment by next-generation sequencing is costly. Here, Saini et al. provide a SNP+STR haplotype reference panel that allows imputation of STRs from SNP array data.

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Autores principales:	Shubham Saini, Ileena Mitra, Nima Mousavi, Stephanie Feupe Fotsing, Melissa Gymrek
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9f8d4564b6244aad87e5c7da7129b2db
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spelling	oai:doaj.org-article:9f8d4564b6244aad87e5c7da7129b2db2021-12-02T16:56:55ZA reference haplotype panel for genome-wide imputation of short tandem repeats10.1038/s41467-018-06694-02041-1723https://doaj.org/article/9f8d4564b6244aad87e5c7da7129b2db2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06694-0https://doaj.org/toc/2041-1723Short-tandem repeats (STR), similar to single nucleotide polymorphisms (SNP), contribute to complex traits, but their ascertainment by next-generation sequencing is costly. Here, Saini et al. provide a SNP+STR haplotype reference panel that allows imputation of STRs from SNP array data.Shubham SainiIleena MitraNima MousaviStephanie Feupe FotsingMelissa GymrekNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Shubham Saini Ileena Mitra Nima Mousavi Stephanie Feupe Fotsing Melissa Gymrek A reference haplotype panel for genome-wide imputation of short tandem repeats
description	Short-tandem repeats (STR), similar to single nucleotide polymorphisms (SNP), contribute to complex traits, but their ascertainment by next-generation sequencing is costly. Here, Saini et al. provide a SNP+STR haplotype reference panel that allows imputation of STRs from SNP array data.
format	article
author	Shubham Saini Ileena Mitra Nima Mousavi Stephanie Feupe Fotsing Melissa Gymrek
author_facet	Shubham Saini Ileena Mitra Nima Mousavi Stephanie Feupe Fotsing Melissa Gymrek
author_sort	Shubham Saini
title	A reference haplotype panel for genome-wide imputation of short tandem repeats
title_short	A reference haplotype panel for genome-wide imputation of short tandem repeats
title_full	A reference haplotype panel for genome-wide imputation of short tandem repeats
title_fullStr	A reference haplotype panel for genome-wide imputation of short tandem repeats
title_full_unstemmed	A reference haplotype panel for genome-wide imputation of short tandem repeats
title_sort	reference haplotype panel for genome-wide imputation of short tandem repeats
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/9f8d4564b6244aad87e5c7da7129b2db
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A reference haplotype panel for genome-wide imputation of short tandem repeats

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