Transcranial magnetic stimulation for the treatment of major depression

Philip G Janicak, Mehmet E DokucuDepartment of Psychiatry and Behavioral Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, USAAbstract: Major depression is often difficult to diagnose accurately. Even when the diagnosis is properly made, standard treatment approaches (eg,...

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Autores principales:	Janicak PG, Dokucu ME
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/9f92ea46d73040fca33fad49fae71885
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spelling	oai:doaj.org-article:9f92ea46d73040fca33fad49fae718852021-12-02T01:18:49ZTranscranial magnetic stimulation for the treatment of major depression1178-2021https://doaj.org/article/9f92ea46d73040fca33fad49fae718852015-06-01T00:00:00Zhttp://www.dovepress.com/transcranial-magnetic-stimulation-for-the-treatment-of-major-depressio-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Philip G Janicak, Mehmet E DokucuDepartment of Psychiatry and Behavioral Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, USAAbstract: Major depression is often difficult to diagnose accurately. Even when the diagnosis is properly made, standard treatment approaches (eg, psychotherapy, medications, or their combination) are often inadequate to control acute symptoms or maintain initial benefit. Additional obstacles involve safety and tolerability problems, which frequently preclude an adequate course of treatment. This leaves an important gap in our ability to properly manage major depression in a substantial proportion of patients, leaving them vulnerable to ensuing complications (eg, employment-related disability, increased risk of suicide, comorbid medical disorders, and substance abuse). Thus, there is a need for more effective and better tolerated approaches. Transcranial magnetic stimulation is a neuromodulation technique increasingly used to partly fill this therapeutic void. In the context of treating depression, we critically review the development of transcranial magnetic stimulation, focusing on the results of controlled and pragmatic trials for depression, which consider its efficacy, safety, and tolerability.Keywords: electroconvulsive therapy, treatment-resistant depression, major depression, transcranial magnetic stimulationJanicak PGDokucu MEDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2015, Iss default, Pp 1549-1560 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Janicak PG Dokucu ME Transcranial magnetic stimulation for the treatment of major depression
description	Philip G Janicak, Mehmet E DokucuDepartment of Psychiatry and Behavioral Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, USAAbstract: Major depression is often difficult to diagnose accurately. Even when the diagnosis is properly made, standard treatment approaches (eg, psychotherapy, medications, or their combination) are often inadequate to control acute symptoms or maintain initial benefit. Additional obstacles involve safety and tolerability problems, which frequently preclude an adequate course of treatment. This leaves an important gap in our ability to properly manage major depression in a substantial proportion of patients, leaving them vulnerable to ensuing complications (eg, employment-related disability, increased risk of suicide, comorbid medical disorders, and substance abuse). Thus, there is a need for more effective and better tolerated approaches. Transcranial magnetic stimulation is a neuromodulation technique increasingly used to partly fill this therapeutic void. In the context of treating depression, we critically review the development of transcranial magnetic stimulation, focusing on the results of controlled and pragmatic trials for depression, which consider its efficacy, safety, and tolerability.Keywords: electroconvulsive therapy, treatment-resistant depression, major depression, transcranial magnetic stimulation
format	article
author	Janicak PG Dokucu ME
author_facet	Janicak PG Dokucu ME
author_sort	Janicak PG
title	Transcranial magnetic stimulation for the treatment of major depression
title_short	Transcranial magnetic stimulation for the treatment of major depression
title_full	Transcranial magnetic stimulation for the treatment of major depression
title_fullStr	Transcranial magnetic stimulation for the treatment of major depression
title_full_unstemmed	Transcranial magnetic stimulation for the treatment of major depression
title_sort	transcranial magnetic stimulation for the treatment of major depression
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/9f92ea46d73040fca33fad49fae71885
work_keys_str_mv	AT janicakpg transcranialmagneticstimulationforthetreatmentofmajordepression AT dokucume transcranialmagneticstimulationforthetreatmentofmajordepression
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Transcranial magnetic stimulation for the treatment of major depression

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