Persistent akathisia masquerading as agitated depression after use of ziprasidone in the treatment of bipolar depression

Thomas M Penders,1 Salina Agarwal,2 Rachel Rohaidy11Department of Psychiatric Medicine, Brody School of Medicine, East Carolina University, Greenville, NC, USA; 2Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USAAbstract: There has been increasin...

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Autores principales:	Penders TM, Agarwal S, Rohaidy RV
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/9f94ced29c31417d8efb2ed5cf77033b
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spelling	oai:doaj.org-article:9f94ced29c31417d8efb2ed5cf77033b2021-12-02T07:43:39ZPersistent akathisia masquerading as agitated depression after use of ziprasidone in the treatment of bipolar depression1176-63281178-2021https://doaj.org/article/9f94ced29c31417d8efb2ed5cf77033b2013-04-01T00:00:00Zhttp://www.dovepress.com/persistent-akathisia-masquerading-as-agitated-depression-after-use-of--a12657https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Thomas M Penders,1 Salina Agarwal,2 Rachel Rohaidy11Department of Psychiatric Medicine, Brody School of Medicine, East Carolina University, Greenville, NC, USA; 2Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USAAbstract: There has been increasing recognition that the second-generation antipsychotic drugs can produce extrapyramidal side effects. This case reports the development of severe akathisia in a patient being treated with ziprasidone for bipolar depression. The case illustrates that this symptom can be easily mistaken for worsening agitated depression. Akathisia may produce considerable distress and elevate suicide risk. Such symptoms may persist for weeks and be refractory to discontinuation of the offending agent or to pharmacological interventions commonly used to mitigate this reaction.Keywords: extrapyramidal, second-generation, affective, antipsychotic, suicide, mood disorderPenders TMAgarwal SRohaidy RVDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2013, Iss default, Pp 463-465 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Penders TM Agarwal S Rohaidy RV Persistent akathisia masquerading as agitated depression after use of ziprasidone in the treatment of bipolar depression
description	Thomas M Penders,1 Salina Agarwal,2 Rachel Rohaidy11Department of Psychiatric Medicine, Brody School of Medicine, East Carolina University, Greenville, NC, USA; 2Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USAAbstract: There has been increasing recognition that the second-generation antipsychotic drugs can produce extrapyramidal side effects. This case reports the development of severe akathisia in a patient being treated with ziprasidone for bipolar depression. The case illustrates that this symptom can be easily mistaken for worsening agitated depression. Akathisia may produce considerable distress and elevate suicide risk. Such symptoms may persist for weeks and be refractory to discontinuation of the offending agent or to pharmacological interventions commonly used to mitigate this reaction.Keywords: extrapyramidal, second-generation, affective, antipsychotic, suicide, mood disorder
format	article
author	Penders TM Agarwal S Rohaidy RV
author_facet	Penders TM Agarwal S Rohaidy RV
author_sort	Penders TM
title	Persistent akathisia masquerading as agitated depression after use of ziprasidone in the treatment of bipolar depression
title_short	Persistent akathisia masquerading as agitated depression after use of ziprasidone in the treatment of bipolar depression
title_full	Persistent akathisia masquerading as agitated depression after use of ziprasidone in the treatment of bipolar depression
title_fullStr	Persistent akathisia masquerading as agitated depression after use of ziprasidone in the treatment of bipolar depression
title_full_unstemmed	Persistent akathisia masquerading as agitated depression after use of ziprasidone in the treatment of bipolar depression
title_sort	persistent akathisia masquerading as agitated depression after use of ziprasidone in the treatment of bipolar depression
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/9f94ced29c31417d8efb2ed5cf77033b
work_keys_str_mv	AT penderstm persistentakathisiamasqueradingasagitateddepressionafteruseofziprasidoneinthetreatmentofbipolardepression AT agarwals persistentakathisiamasqueradingasagitateddepressionafteruseofziprasidoneinthetreatmentofbipolardepression AT rohaidyrv persistentakathisiamasqueradingasagitateddepressionafteruseofziprasidoneinthetreatmentofbipolardepression
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Persistent akathisia masquerading as agitated depression after use of ziprasidone in the treatment of bipolar depression

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