Increased immunogenicity and protective efficacy of influenza M2e fused to a tetramerizing protein.

Increased immunogenicity and protective efficacy of influenza M2e fused to a tetramerizing protein.

The ectodomain of the matrix 2 protein (M2e) of influenza A virus represents an attractive target for developing a universal influenza A vaccine, with its sequence being highly conserved amongst human variants of this virus. With the aim of targeting conformational epitopes presumably shared by dive...

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Autores principales: Anne-Marie Carola Andersson, Kjell O Håkansson, Benjamin Anderschou Holbech Jensen, Dennis Christensen, Peter Andersen, Allan Randrup Thomsen, Jan Pravsgaard Christensen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/9fcc58fe31204fd5913bf95deb263eb9
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