Evidence for model-based computations in the human amygdala during Pavlovian conditioning.

Contemporary computational accounts of instrumental conditioning have emphasized a role for a model-based system in which values are computed with reference to a rich model of the structure of the world, and a model-free system in which values are updated without encoding such structure. Much less s...

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Autores principales:	Charlotte Prévost, Daniel McNamee, Ryan K Jessup, Peter Bossaerts, John P O'Doherty
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/9fd39b6f5bc14966a4bcc382e0344123
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spelling	oai:doaj.org-article:9fd39b6f5bc14966a4bcc382e03441232021-11-18T05:52:26ZEvidence for model-based computations in the human amygdala during Pavlovian conditioning.1553-734X1553-735810.1371/journal.pcbi.1002918https://doaj.org/article/9fd39b6f5bc14966a4bcc382e03441232013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23436990/?tool=EBIhttps://doaj.org/toc/1553-734Xhttps://doaj.org/toc/1553-7358Contemporary computational accounts of instrumental conditioning have emphasized a role for a model-based system in which values are computed with reference to a rich model of the structure of the world, and a model-free system in which values are updated without encoding such structure. Much less studied is the possibility of a similar distinction operating at the level of Pavlovian conditioning. In the present study, we scanned human participants while they participated in a Pavlovian conditioning task with a simple structure while measuring activity in the human amygdala using a high-resolution fMRI protocol. After fitting a model-based algorithm and a variety of model-free algorithms to the fMRI data, we found evidence for the superiority of a model-based algorithm in accounting for activity in the amygdala compared to the model-free counterparts. These findings support an important role for model-based algorithms in describing the processes underpinning Pavlovian conditioning, as well as providing evidence of a role for the human amygdala in model-based inference.Charlotte PrévostDaniel McNameeRyan K JessupPeter BossaertsJohn P O'DohertyPublic Library of Science (PLoS)articleBiology (General)QH301-705.5ENPLoS Computational Biology, Vol 9, Iss 2, p e1002918 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Charlotte Prévost Daniel McNamee Ryan K Jessup Peter Bossaerts John P O'Doherty Evidence for model-based computations in the human amygdala during Pavlovian conditioning.
description	Contemporary computational accounts of instrumental conditioning have emphasized a role for a model-based system in which values are computed with reference to a rich model of the structure of the world, and a model-free system in which values are updated without encoding such structure. Much less studied is the possibility of a similar distinction operating at the level of Pavlovian conditioning. In the present study, we scanned human participants while they participated in a Pavlovian conditioning task with a simple structure while measuring activity in the human amygdala using a high-resolution fMRI protocol. After fitting a model-based algorithm and a variety of model-free algorithms to the fMRI data, we found evidence for the superiority of a model-based algorithm in accounting for activity in the amygdala compared to the model-free counterparts. These findings support an important role for model-based algorithms in describing the processes underpinning Pavlovian conditioning, as well as providing evidence of a role for the human amygdala in model-based inference.
format	article
author	Charlotte Prévost Daniel McNamee Ryan K Jessup Peter Bossaerts John P O'Doherty
author_facet	Charlotte Prévost Daniel McNamee Ryan K Jessup Peter Bossaerts John P O'Doherty
author_sort	Charlotte Prévost
title	Evidence for model-based computations in the human amygdala during Pavlovian conditioning.
title_short	Evidence for model-based computations in the human amygdala during Pavlovian conditioning.
title_full	Evidence for model-based computations in the human amygdala during Pavlovian conditioning.
title_fullStr	Evidence for model-based computations in the human amygdala during Pavlovian conditioning.
title_full_unstemmed	Evidence for model-based computations in the human amygdala during Pavlovian conditioning.
title_sort	evidence for model-based computations in the human amygdala during pavlovian conditioning.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/9fd39b6f5bc14966a4bcc382e0344123
work_keys_str_mv	AT charlotteprevost evidenceformodelbasedcomputationsinthehumanamygdaladuringpavlovianconditioning AT danielmcnamee evidenceformodelbasedcomputationsinthehumanamygdaladuringpavlovianconditioning AT ryankjessup evidenceformodelbasedcomputationsinthehumanamygdaladuringpavlovianconditioning AT peterbossaerts evidenceformodelbasedcomputationsinthehumanamygdaladuringpavlovianconditioning AT johnpodoherty evidenceformodelbasedcomputationsinthehumanamygdaladuringpavlovianconditioning
_version_	1718424746479058944

Evidence for model-based computations in the human amygdala during Pavlovian conditioning.

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