Intratumoral Heterogeneity Promotes Collective Cancer Invasion through NOTCH1 Variation
Cellular and molecular heterogeneity within tumors has long been associated with the progression of cancer to an aggressive phenotype and a poor prognosis. However, how such intratumoral heterogeneity contributes to the invasiveness of cancer is largely unknown. Here, using a tumor bioengineering ap...
Guardado en:
Autores principales: | Peter Torab, Yue Yan, Mona Ahmed, Hironobu Yamashita, Joshua I. Warrick, Jay D. Raman, David J. DeGraff, Pak Kin Wong |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/9fd3d75d6c6547998b2dfb18ad573bc7 |
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