Assessment of Oral Chemotherapy Nonadherence in Chronic Myeloid Leukemia Patients Using Brief Measures in Community Cancer Clinics: A Pilot Study

The purpose of this pilot study was to assess Chronic Myeloid Leukemia (CML) patients’ adherence to, beliefs about, and barriers to oral anticancer agents (OAC) using brief self-report measures in community-based cancer clinics. Patients completed a structured interview including a health literacy a...

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Autores principales:	Terry C. Davis, Connie L. Arnold, Glenn Mills, Glenn J. Lesser, W. Mark Brown, Richard Schulz, Kathryn E. Weaver, Pamala A. Pawloski
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	chronic myelogenous leukemia antineoplastic agents medication adherence self-report health literacy Medicine R
Acceso en línea:	https://doaj.org/article/9fd899074d48423bbfe08aae834277a1
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spelling	oai:doaj.org-article:9fd899074d48423bbfe08aae834277a12021-11-11T16:11:47ZAssessment of Oral Chemotherapy Nonadherence in Chronic Myeloid Leukemia Patients Using Brief Measures in Community Cancer Clinics: A Pilot Study10.3390/ijerph1821110451660-46011661-7827https://doaj.org/article/9fd899074d48423bbfe08aae834277a12021-10-01T00:00:00Zhttps://www.mdpi.com/1660-4601/18/21/11045https://doaj.org/toc/1661-7827https://doaj.org/toc/1660-4601The purpose of this pilot study was to assess Chronic Myeloid Leukemia (CML) patients’ adherence to, beliefs about, and barriers to oral anticancer agents (OAC) using brief self-report measures in community-based cancer clinics. Patients completed a structured interview including a health literacy assessment, a Brief Medication Questionnaire, two single-item self-report adherence questions, and the Medications Adherence Reasons Scale. Of the 86 participants, 88.4% were white; 55.8% male; mean age, 58.7 years; and 22.1% had limited health literacy. Nonadherence (missing at least one dose in the last week) was reported by 18.6% of participants and associated (<i>p</i> < 0.003) with less-than-excellent perceived ability to take CML medications (16.3%). Black participants reported more difficulty taking CML medications than white participants (28.6% vs. 8.3%, <i>p</i> = 0.053). Among all participants, 43.0% reported their CML medicine was ineffective and 24.4% that taking CML pills was somewhat to very hard. The most common reasons for missing a dose were simply missed it (24.4%) and side effects (18.6%). Most patients perceived their ability to take CML medication was good to excellent, yet nearly one in five reported missing at least one dose in the last week. Brief, no-cost self-report assessments to screen CML patients’ OAC adherence, barriers, and beliefs could facilitate counseling in busy community cancer clinics.Terry C. DavisConnie L. ArnoldGlenn MillsGlenn J. LesserW. Mark BrownRichard SchulzKathryn E. WeaverPamala A. PawloskiMDPI AGarticlechronic myelogenous leukemiaantineoplastic agentsmedication adherenceself-reporthealth literacyMedicineRENInternational Journal of Environmental Research and Public Health, Vol 18, Iss 11045, p 11045 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	chronic myelogenous leukemia antineoplastic agents medication adherence self-report health literacy Medicine R
spellingShingle	chronic myelogenous leukemia antineoplastic agents medication adherence self-report health literacy Medicine R Terry C. Davis Connie L. Arnold Glenn Mills Glenn J. Lesser W. Mark Brown Richard Schulz Kathryn E. Weaver Pamala A. Pawloski Assessment of Oral Chemotherapy Nonadherence in Chronic Myeloid Leukemia Patients Using Brief Measures in Community Cancer Clinics: A Pilot Study
description	The purpose of this pilot study was to assess Chronic Myeloid Leukemia (CML) patients’ adherence to, beliefs about, and barriers to oral anticancer agents (OAC) using brief self-report measures in community-based cancer clinics. Patients completed a structured interview including a health literacy assessment, a Brief Medication Questionnaire, two single-item self-report adherence questions, and the Medications Adherence Reasons Scale. Of the 86 participants, 88.4% were white; 55.8% male; mean age, 58.7 years; and 22.1% had limited health literacy. Nonadherence (missing at least one dose in the last week) was reported by 18.6% of participants and associated (<i>p</i> < 0.003) with less-than-excellent perceived ability to take CML medications (16.3%). Black participants reported more difficulty taking CML medications than white participants (28.6% vs. 8.3%, <i>p</i> = 0.053). Among all participants, 43.0% reported their CML medicine was ineffective and 24.4% that taking CML pills was somewhat to very hard. The most common reasons for missing a dose were simply missed it (24.4%) and side effects (18.6%). Most patients perceived their ability to take CML medication was good to excellent, yet nearly one in five reported missing at least one dose in the last week. Brief, no-cost self-report assessments to screen CML patients’ OAC adherence, barriers, and beliefs could facilitate counseling in busy community cancer clinics.
format	article
author	Terry C. Davis Connie L. Arnold Glenn Mills Glenn J. Lesser W. Mark Brown Richard Schulz Kathryn E. Weaver Pamala A. Pawloski
author_facet	Terry C. Davis Connie L. Arnold Glenn Mills Glenn J. Lesser W. Mark Brown Richard Schulz Kathryn E. Weaver Pamala A. Pawloski
author_sort	Terry C. Davis
title	Assessment of Oral Chemotherapy Nonadherence in Chronic Myeloid Leukemia Patients Using Brief Measures in Community Cancer Clinics: A Pilot Study
title_short	Assessment of Oral Chemotherapy Nonadherence in Chronic Myeloid Leukemia Patients Using Brief Measures in Community Cancer Clinics: A Pilot Study
title_full	Assessment of Oral Chemotherapy Nonadherence in Chronic Myeloid Leukemia Patients Using Brief Measures in Community Cancer Clinics: A Pilot Study
title_fullStr	Assessment of Oral Chemotherapy Nonadherence in Chronic Myeloid Leukemia Patients Using Brief Measures in Community Cancer Clinics: A Pilot Study
title_full_unstemmed	Assessment of Oral Chemotherapy Nonadherence in Chronic Myeloid Leukemia Patients Using Brief Measures in Community Cancer Clinics: A Pilot Study
title_sort	assessment of oral chemotherapy nonadherence in chronic myeloid leukemia patients using brief measures in community cancer clinics: a pilot study
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/9fd899074d48423bbfe08aae834277a1
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Assessment of Oral Chemotherapy Nonadherence in Chronic Myeloid Leukemia Patients Using Brief Measures in Community Cancer Clinics: A Pilot Study

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