Total synthesis and antimicrobial evaluation of natural albomycins against clinical pathogens

Albomycins are promising drug candidates for the treatment of bacterial infections. Here, the authors describe the total syntheses of albomycins δ 1, δ 2, and ε, and evaluate their antimicrobial activity, identifying albomycin δ 2 as a strong agent against S. pneumoniae and S. aureus infections.

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Autores principales: Zihua Lin, Xiaobo Xu, Sheng Zhao, Xiaohong Yang, Jian Guo, Qun Zhang, Chunmei Jing, Shawn Chen, Yun He
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/9fd9b36c76ae4c8aa6389a0ec226f920
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