Assisted reproductive technologies are associated with limited epigenetic variation at birth that largely resolves by adulthood

Use of Assisted Reproductive Technologies (ART) is increasing globally but their impact on long term health remains unclear. Here the authors show that ART-conceived individuals show variation in epigenetic profile at birth that largely resolves by adulthood, with no evidence of an impact on long te...

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Autores principales: Boris Novakovic, Sharon Lewis, Jane Halliday, Joanne Kennedy, David P. Burgner, Anna Czajko, Bowon Kim, Alexandra Sexton-Oates, Markus Juonala, Karin Hammarberg, David J. Amor, Lex W. Doyle, Sarath Ranganathan, Liam Welsh, Michael Cheung, John McBain, Robert McLachlan, Richard Saffery
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/a001b8f17ce14b76a01653102a7348a0
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spelling oai:doaj.org-article:a001b8f17ce14b76a01653102a7348a02021-12-02T14:38:42ZAssisted reproductive technologies are associated with limited epigenetic variation at birth that largely resolves by adulthood10.1038/s41467-019-11929-92041-1723https://doaj.org/article/a001b8f17ce14b76a01653102a7348a02019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11929-9https://doaj.org/toc/2041-1723Use of Assisted Reproductive Technologies (ART) is increasing globally but their impact on long term health remains unclear. Here the authors show that ART-conceived individuals show variation in epigenetic profile at birth that largely resolves by adulthood, with no evidence of an impact on long term outcomes.Boris NovakovicSharon LewisJane HallidayJoanne KennedyDavid P. BurgnerAnna CzajkoBowon KimAlexandra Sexton-OatesMarkus JuonalaKarin HammarbergDavid J. AmorLex W. DoyleSarath RanganathanLiam WelshMichael CheungJohn McBainRobert McLachlanRichard SafferyNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Boris Novakovic
Sharon Lewis
Jane Halliday
Joanne Kennedy
David P. Burgner
Anna Czajko
Bowon Kim
Alexandra Sexton-Oates
Markus Juonala
Karin Hammarberg
David J. Amor
Lex W. Doyle
Sarath Ranganathan
Liam Welsh
Michael Cheung
John McBain
Robert McLachlan
Richard Saffery
Assisted reproductive technologies are associated with limited epigenetic variation at birth that largely resolves by adulthood
description Use of Assisted Reproductive Technologies (ART) is increasing globally but their impact on long term health remains unclear. Here the authors show that ART-conceived individuals show variation in epigenetic profile at birth that largely resolves by adulthood, with no evidence of an impact on long term outcomes.
format article
author Boris Novakovic
Sharon Lewis
Jane Halliday
Joanne Kennedy
David P. Burgner
Anna Czajko
Bowon Kim
Alexandra Sexton-Oates
Markus Juonala
Karin Hammarberg
David J. Amor
Lex W. Doyle
Sarath Ranganathan
Liam Welsh
Michael Cheung
John McBain
Robert McLachlan
Richard Saffery
author_facet Boris Novakovic
Sharon Lewis
Jane Halliday
Joanne Kennedy
David P. Burgner
Anna Czajko
Bowon Kim
Alexandra Sexton-Oates
Markus Juonala
Karin Hammarberg
David J. Amor
Lex W. Doyle
Sarath Ranganathan
Liam Welsh
Michael Cheung
John McBain
Robert McLachlan
Richard Saffery
author_sort Boris Novakovic
title Assisted reproductive technologies are associated with limited epigenetic variation at birth that largely resolves by adulthood
title_short Assisted reproductive technologies are associated with limited epigenetic variation at birth that largely resolves by adulthood
title_full Assisted reproductive technologies are associated with limited epigenetic variation at birth that largely resolves by adulthood
title_fullStr Assisted reproductive technologies are associated with limited epigenetic variation at birth that largely resolves by adulthood
title_full_unstemmed Assisted reproductive technologies are associated with limited epigenetic variation at birth that largely resolves by adulthood
title_sort assisted reproductive technologies are associated with limited epigenetic variation at birth that largely resolves by adulthood
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/a001b8f17ce14b76a01653102a7348a0
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