SEIZURES IN CHILDREN WITH LOW GRADE GLIOMA

Seizures are a common presentation of pediatric brain tumors. The incidence of pediatric brain tumor (Age 0-19 years) ranges from 1.12–5.26 cases per 100,000 persons. Low grade gliomas are an important subgroup of pediatric brain tumors causing epilepsy. Low-grade gliomas are largely slow-growing tu...

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Main Authors: Piyush Ostwal, Shanbhag Nandan
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Language:EN
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Published: University of Brawijaya 2021
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Online Access:https://doaj.org/article/a005f780758f40699aac9eb656c8ed93
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spelling oai:doaj.org-article:a005f780758f40699aac9eb656c8ed932021-11-23T03:58:52ZSEIZURES IN CHILDREN WITH LOW GRADE GLIOMA10.21776/ub.mnj.2021.007.01.122407-67242442-5001https://doaj.org/article/a005f780758f40699aac9eb656c8ed932021-01-01T00:00:00Zhttps://mnj.ub.ac.id/index.php/mnj/article/view/479https://doaj.org/toc/2407-6724https://doaj.org/toc/2442-5001Seizures are a common presentation of pediatric brain tumors. The incidence of pediatric brain tumor (Age 0-19 years) ranges from 1.12–5.26 cases per 100,000 persons. Low grade gliomas are an important subgroup of pediatric brain tumors causing epilepsy. Low-grade gliomas are largely slow-growing tumors and the manifestations are dependent on age, location, tumor type, size of tumor and rate of tumor growth. Seizures have been reported in up to 38 % of children with supratentorial tumors. The tumors are identified when work up of patients for epilepsy includes electrophysiological and imaging studies. The primary treatment modality remains surgical excision. Antiepileptic medications are used for control of seizures. Subsequent histopathological diagnosis is important for prognostication. The tumors commonly associated with long-term epilepsy in various studies were ganglioglioma, dysembryoplastic neuroepithelial tumor, pilocytic astrocytoma and pilocytic xanthoastrocytoma. The outcome of surgery with regards to seizure control is generally good. Though concomitantly antiepileptic medications will be needed for most of them. An attempt is made in this review to summarize the epidemiology, clinical features, pathology and treatment aspects of pediatric low grade gliomas presenting with seizures.Piyush OstwalShanbhag NandanUniversity of Brawijayaarticleseizureslow grade gliomapediatric epilepsybrain tumorMedicineRNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571ENIDMalang Neurology Journal, Vol 7, Iss 1, Pp 60-65 (2021)
institution DOAJ
collection DOAJ
language EN
ID
topic seizures
low grade glioma
pediatric epilepsy
brain tumor
Medicine
R
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
spellingShingle seizures
low grade glioma
pediatric epilepsy
brain tumor
Medicine
R
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Piyush Ostwal
Shanbhag Nandan
SEIZURES IN CHILDREN WITH LOW GRADE GLIOMA
description Seizures are a common presentation of pediatric brain tumors. The incidence of pediatric brain tumor (Age 0-19 years) ranges from 1.12–5.26 cases per 100,000 persons. Low grade gliomas are an important subgroup of pediatric brain tumors causing epilepsy. Low-grade gliomas are largely slow-growing tumors and the manifestations are dependent on age, location, tumor type, size of tumor and rate of tumor growth. Seizures have been reported in up to 38 % of children with supratentorial tumors. The tumors are identified when work up of patients for epilepsy includes electrophysiological and imaging studies. The primary treatment modality remains surgical excision. Antiepileptic medications are used for control of seizures. Subsequent histopathological diagnosis is important for prognostication. The tumors commonly associated with long-term epilepsy in various studies were ganglioglioma, dysembryoplastic neuroepithelial tumor, pilocytic astrocytoma and pilocytic xanthoastrocytoma. The outcome of surgery with regards to seizure control is generally good. Though concomitantly antiepileptic medications will be needed for most of them. An attempt is made in this review to summarize the epidemiology, clinical features, pathology and treatment aspects of pediatric low grade gliomas presenting with seizures.
format article
author Piyush Ostwal
Shanbhag Nandan
author_facet Piyush Ostwal
Shanbhag Nandan
author_sort Piyush Ostwal
title SEIZURES IN CHILDREN WITH LOW GRADE GLIOMA
title_short SEIZURES IN CHILDREN WITH LOW GRADE GLIOMA
title_full SEIZURES IN CHILDREN WITH LOW GRADE GLIOMA
title_fullStr SEIZURES IN CHILDREN WITH LOW GRADE GLIOMA
title_full_unstemmed SEIZURES IN CHILDREN WITH LOW GRADE GLIOMA
title_sort seizures in children with low grade glioma
publisher University of Brawijaya
publishDate 2021
url https://doaj.org/article/a005f780758f40699aac9eb656c8ed93
work_keys_str_mv AT piyushostwal seizuresinchildrenwithlowgradeglioma
AT shanbhagnandan seizuresinchildrenwithlowgradeglioma
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