Chronic rejection pathology after orthotopic lung transplantation in mice: the development of a murine BOS model and its drawbacks.

Chronic rejection pathology after orthotopic lung transplantation in mice: the development of a murine BOS model and its drawbacks.

Almost all animal models for chronic rejection (CR) after lung transplantation (LTx) fail to resemble the human situation. It was our attempt to develop a representative model of CR in mice. Orthotopic LTx was performed in allografts receiving daily immunosuppression with steroids and cyclosporine....

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Main Authors: Stéphanie De Vleeschauwer, Wolfgang Jungraithmayr, Shana Wauters, Stijn Willems, Manuela Rinaldi, Annemie Vaneylen, Stijn Verleden, Anna Willems-Widyastuti, Ken Bracke, Guy Brusselle, Erik Verbeken, Dirk Van Raemdonck, Geert Verleden, Bart Vanaudenaerde
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/a00fb88bf8524eb59e6a4b986d06d7dd
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https://doaj.org/article/a00fb88bf8524eb59e6a4b986d06d7dd

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