Role of DWI in evaluation of HCC after radiofrequency ablation compared to dynamic MRI using MRI (3 T)

Abstract Background The purpose of this study was to investigate the diagnostic performance of diffusion weight imaging (DWI), apparent diffusion coefficient (ADC) map, normalized ADC liver, and normalized ADC spleen compared to the dynamic contrast-enhanced MRI (DCE-MRI) in the evaluation of residu...

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Autores principales:	Bahaa Mohamed Elrefaey Hasan, Hanaa Abd ElKader Abd ElHamid, Nivan Hany Khater, Waseem ElGendy, Ahmed S. Abdelrahman
Formato:	article
Lenguaje:	EN
Publicado:	SpringerOpen 2021
Materias:	RFA HCC DCE-MRI DWI ADC Normalized ADC Medical physics. Medical radiology. Nuclear medicine R895-920
Acceso en línea:	https://doaj.org/article/a01673adb80e409f9933168f165b0639
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spelling	oai:doaj.org-article:a01673adb80e409f9933168f165b06392021-11-14T12:27:05ZRole of DWI in evaluation of HCC after radiofrequency ablation compared to dynamic MRI using MRI (3 T)10.1186/s43055-021-00647-22090-4762https://doaj.org/article/a01673adb80e409f9933168f165b06392021-11-01T00:00:00Zhttps://doi.org/10.1186/s43055-021-00647-2https://doaj.org/toc/2090-4762Abstract Background The purpose of this study was to investigate the diagnostic performance of diffusion weight imaging (DWI), apparent diffusion coefficient (ADC) map, normalized ADC liver, and normalized ADC spleen compared to the dynamic contrast-enhanced MRI (DCE-MRI) in the evaluation of residual hepatocellular carcinoma (HCC) after radiofrequency ablation (RFA) using 3 T (T) magnetic resonance imaging (MRI). Results A prospective study was performed on 40 patients with radiofrequency-ablated HCC, and 15 (37.5%) patients had viable lesion post-RFA, while 25 (62.5%) had non-viable lesions. DCE-MRI had a sensitivity, specificity, and accuracy of 100%, 100%, and 100%, respectively, compared to DWI which had a sensitivity, specificity, and accuracy of 80%, 88%, and 85%, respectively, for identifying post-RFA viable HCC. The sensitivity, specificity, and accuracy of ADC at a cutoff value of 1.01 × 10−3 mm2/s were 80%, 100%, and 97.1%, respectively. The optimal cutoff value of normalized ADC liver was 0.81 with a sensitivity of 73.3%, specificity of 96%, and accuracy of 92.8%. The sensitivity, specificity, and accuracy of normalized ADC spleen at a cutoff value of 1.22 were 80%, 92%, and 91.1%, respectively. Conclusions DWI-MRI is a reliable technique for assessing HCC after radiofrequency ablation. DWI-MRI with ADC may be used as an alternate sequence for assessing radiofrequency-ablated lesions in individuals who have a contraindication to the contrast media, and the normalized ADC value may be of additional benefit.Bahaa Mohamed Elrefaey HasanHanaa Abd ElKader Abd ElHamidNivan Hany KhaterWaseem ElGendyAhmed S. AbdelrahmanSpringerOpenarticleRFAHCCDCE-MRIDWIADCNormalized ADCMedical physics. Medical radiology. Nuclear medicineR895-920ENThe Egyptian Journal of Radiology and Nuclear Medicine, Vol 52, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	RFA HCC DCE-MRI DWI ADC Normalized ADC Medical physics. Medical radiology. Nuclear medicine R895-920
spellingShingle	RFA HCC DCE-MRI DWI ADC Normalized ADC Medical physics. Medical radiology. Nuclear medicine R895-920 Bahaa Mohamed Elrefaey Hasan Hanaa Abd ElKader Abd ElHamid Nivan Hany Khater Waseem ElGendy Ahmed S. Abdelrahman Role of DWI in evaluation of HCC after radiofrequency ablation compared to dynamic MRI using MRI (3 T)
description	Abstract Background The purpose of this study was to investigate the diagnostic performance of diffusion weight imaging (DWI), apparent diffusion coefficient (ADC) map, normalized ADC liver, and normalized ADC spleen compared to the dynamic contrast-enhanced MRI (DCE-MRI) in the evaluation of residual hepatocellular carcinoma (HCC) after radiofrequency ablation (RFA) using 3 T (T) magnetic resonance imaging (MRI). Results A prospective study was performed on 40 patients with radiofrequency-ablated HCC, and 15 (37.5%) patients had viable lesion post-RFA, while 25 (62.5%) had non-viable lesions. DCE-MRI had a sensitivity, specificity, and accuracy of 100%, 100%, and 100%, respectively, compared to DWI which had a sensitivity, specificity, and accuracy of 80%, 88%, and 85%, respectively, for identifying post-RFA viable HCC. The sensitivity, specificity, and accuracy of ADC at a cutoff value of 1.01 × 10−3 mm2/s were 80%, 100%, and 97.1%, respectively. The optimal cutoff value of normalized ADC liver was 0.81 with a sensitivity of 73.3%, specificity of 96%, and accuracy of 92.8%. The sensitivity, specificity, and accuracy of normalized ADC spleen at a cutoff value of 1.22 were 80%, 92%, and 91.1%, respectively. Conclusions DWI-MRI is a reliable technique for assessing HCC after radiofrequency ablation. DWI-MRI with ADC may be used as an alternate sequence for assessing radiofrequency-ablated lesions in individuals who have a contraindication to the contrast media, and the normalized ADC value may be of additional benefit.
format	article
author	Bahaa Mohamed Elrefaey Hasan Hanaa Abd ElKader Abd ElHamid Nivan Hany Khater Waseem ElGendy Ahmed S. Abdelrahman
author_facet	Bahaa Mohamed Elrefaey Hasan Hanaa Abd ElKader Abd ElHamid Nivan Hany Khater Waseem ElGendy Ahmed S. Abdelrahman
author_sort	Bahaa Mohamed Elrefaey Hasan
title	Role of DWI in evaluation of HCC after radiofrequency ablation compared to dynamic MRI using MRI (3 T)
title_short	Role of DWI in evaluation of HCC after radiofrequency ablation compared to dynamic MRI using MRI (3 T)
title_full	Role of DWI in evaluation of HCC after radiofrequency ablation compared to dynamic MRI using MRI (3 T)
title_fullStr	Role of DWI in evaluation of HCC after radiofrequency ablation compared to dynamic MRI using MRI (3 T)
title_full_unstemmed	Role of DWI in evaluation of HCC after radiofrequency ablation compared to dynamic MRI using MRI (3 T)
title_sort	role of dwi in evaluation of hcc after radiofrequency ablation compared to dynamic mri using mri (3 t)
publisher	SpringerOpen
publishDate	2021
url	https://doaj.org/article/a01673adb80e409f9933168f165b0639
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Role of DWI in evaluation of HCC after radiofrequency ablation compared to dynamic MRI using MRI (3 T)

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