Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice

Current methods for acquiring dissemination kinetics of rare circulating tumor cells (CTCs) that form metastases have several limitations. Here, the authors show an approach for measuring endogenous CTC kinetics by continuously exchanging CTC-containing blood between un-anesthetized, tumor-bearing m...

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Autores principales:	Bashar Hamza, Alex B. Miller, Lara Meier, Max Stockslager, Sheng Rong Ng, Emily M. King, Lin Lin, Kelsey L. DeGouveia, Nolawit Mulugeta, Nicholas L. Calistri, Haley Strouf, Christina Bray, Felicia Rodriguez, William A. Freed-Pastor, Christopher R. Chin, Grissel C. Jaramillo, Megan L. Burger, Robert A. Weinberg, Alex K. Shalek, Tyler Jacks, Scott R. Manalis
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a01832348b58404486e05ba5132c7532
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spelling	oai:doaj.org-article:a01832348b58404486e05ba5132c75322021-12-02T18:51:37ZMeasuring kinetics and metastatic propensity of CTCs by blood exchange between mice10.1038/s41467-021-25917-52041-1723https://doaj.org/article/a01832348b58404486e05ba5132c75322021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25917-5https://doaj.org/toc/2041-1723Current methods for acquiring dissemination kinetics of rare circulating tumor cells (CTCs) that form metastases have several limitations. Here, the authors show an approach for measuring endogenous CTC kinetics by continuously exchanging CTC-containing blood between un-anesthetized, tumor-bearing mice and healthy, tumor-free counterparts.Bashar HamzaAlex B. MillerLara MeierMax StockslagerSheng Rong NgEmily M. KingLin LinKelsey L. DeGouveiaNolawit MulugetaNicholas L. CalistriHaley StroufChristina BrayFelicia RodriguezWilliam A. Freed-PastorChristopher R. ChinGrissel C. JaramilloMegan L. BurgerRobert A. WeinbergAlex K. ShalekTyler JacksScott R. ManalisNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Bashar Hamza Alex B. Miller Lara Meier Max Stockslager Sheng Rong Ng Emily M. King Lin Lin Kelsey L. DeGouveia Nolawit Mulugeta Nicholas L. Calistri Haley Strouf Christina Bray Felicia Rodriguez William A. Freed-Pastor Christopher R. Chin Grissel C. Jaramillo Megan L. Burger Robert A. Weinberg Alex K. Shalek Tyler Jacks Scott R. Manalis Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice
description	Current methods for acquiring dissemination kinetics of rare circulating tumor cells (CTCs) that form metastases have several limitations. Here, the authors show an approach for measuring endogenous CTC kinetics by continuously exchanging CTC-containing blood between un-anesthetized, tumor-bearing mice and healthy, tumor-free counterparts.
format	article
author	Bashar Hamza Alex B. Miller Lara Meier Max Stockslager Sheng Rong Ng Emily M. King Lin Lin Kelsey L. DeGouveia Nolawit Mulugeta Nicholas L. Calistri Haley Strouf Christina Bray Felicia Rodriguez William A. Freed-Pastor Christopher R. Chin Grissel C. Jaramillo Megan L. Burger Robert A. Weinberg Alex K. Shalek Tyler Jacks Scott R. Manalis
author_facet	Bashar Hamza Alex B. Miller Lara Meier Max Stockslager Sheng Rong Ng Emily M. King Lin Lin Kelsey L. DeGouveia Nolawit Mulugeta Nicholas L. Calistri Haley Strouf Christina Bray Felicia Rodriguez William A. Freed-Pastor Christopher R. Chin Grissel C. Jaramillo Megan L. Burger Robert A. Weinberg Alex K. Shalek Tyler Jacks Scott R. Manalis
author_sort	Bashar Hamza
title	Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice
title_short	Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice
title_full	Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice
title_fullStr	Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice
title_full_unstemmed	Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice
title_sort	measuring kinetics and metastatic propensity of ctcs by blood exchange between mice
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/a01832348b58404486e05ba5132c7532
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Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice

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