Cell-permeable organic fluorescent probes for live-cell long-term super-resolution imaging reveal lysosome-mitochondrion interactions

Studying interactions between lysosomes and mitochondria in living cells is difficult due to the limitations of existing probes. Here, the authors develop new cell-permeable fluorescent probes to image the dynamics of lysosomes and their physical interactions with mitochondria using super-resolution...

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Autores principales:	Yubing Han, Meihua Li, Fengwu Qiu, Meng Zhang, Yu-Hui Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a01875f9f7504c78af1afc7a3ae2afcd
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spelling	oai:doaj.org-article:a01875f9f7504c78af1afc7a3ae2afcd2021-12-02T15:38:34ZCell-permeable organic fluorescent probes for live-cell long-term super-resolution imaging reveal lysosome-mitochondrion interactions10.1038/s41467-017-01503-62041-1723https://doaj.org/article/a01875f9f7504c78af1afc7a3ae2afcd2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01503-6https://doaj.org/toc/2041-1723Studying interactions between lysosomes and mitochondria in living cells is difficult due to the limitations of existing probes. Here, the authors develop new cell-permeable fluorescent probes to image the dynamics of lysosomes and their physical interactions with mitochondria using super-resolution microscopy.Yubing HanMeihua LiFengwu QiuMeng ZhangYu-Hui ZhangNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yubing Han Meihua Li Fengwu Qiu Meng Zhang Yu-Hui Zhang Cell-permeable organic fluorescent probes for live-cell long-term super-resolution imaging reveal lysosome-mitochondrion interactions
description	Studying interactions between lysosomes and mitochondria in living cells is difficult due to the limitations of existing probes. Here, the authors develop new cell-permeable fluorescent probes to image the dynamics of lysosomes and their physical interactions with mitochondria using super-resolution microscopy.
format	article
author	Yubing Han Meihua Li Fengwu Qiu Meng Zhang Yu-Hui Zhang
author_facet	Yubing Han Meihua Li Fengwu Qiu Meng Zhang Yu-Hui Zhang
author_sort	Yubing Han
title	Cell-permeable organic fluorescent probes for live-cell long-term super-resolution imaging reveal lysosome-mitochondrion interactions
title_short	Cell-permeable organic fluorescent probes for live-cell long-term super-resolution imaging reveal lysosome-mitochondrion interactions
title_full	Cell-permeable organic fluorescent probes for live-cell long-term super-resolution imaging reveal lysosome-mitochondrion interactions
title_fullStr	Cell-permeable organic fluorescent probes for live-cell long-term super-resolution imaging reveal lysosome-mitochondrion interactions
title_full_unstemmed	Cell-permeable organic fluorescent probes for live-cell long-term super-resolution imaging reveal lysosome-mitochondrion interactions
title_sort	cell-permeable organic fluorescent probes for live-cell long-term super-resolution imaging reveal lysosome-mitochondrion interactions
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/a01875f9f7504c78af1afc7a3ae2afcd
work_keys_str_mv	AT yubinghan cellpermeableorganicfluorescentprobesforlivecelllongtermsuperresolutionimagingreveallysosomemitochondrioninteractions AT meihuali cellpermeableorganicfluorescentprobesforlivecelllongtermsuperresolutionimagingreveallysosomemitochondrioninteractions AT fengwuqiu cellpermeableorganicfluorescentprobesforlivecelllongtermsuperresolutionimagingreveallysosomemitochondrioninteractions AT mengzhang cellpermeableorganicfluorescentprobesforlivecelllongtermsuperresolutionimagingreveallysosomemitochondrioninteractions AT yuhuizhang cellpermeableorganicfluorescentprobesforlivecelllongtermsuperresolutionimagingreveallysosomemitochondrioninteractions
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Cell-permeable organic fluorescent probes for live-cell long-term super-resolution imaging reveal lysosome-mitochondrion interactions

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