Rhabdomyosarcoma of the uterus in an adult patient with osteopetrosis: a case report

Abstract Background Uterine sarcoma accounts for 3–7% of uterine malignant neoplasms. It is more aggressive than epithelial neoplasms, and patients have a poor prognosis. Rhabdomyosarcoma is classified as a heterologous uterine sarcoma. It is the most common soft tissue malignancy in children while...

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Autores principales:	Soheila Aminimoghaddam, Ali Rahbari, Roghayeh Pourali
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Rhabdomyosarcoma Uterus Sarcoma Medicine R
Acceso en línea:	https://doaj.org/article/a02fb4f9b6ec4eefa9824c8b0a68c3fb
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spelling	oai:doaj.org-article:a02fb4f9b6ec4eefa9824c8b0a68c3fb2021-11-28T12:37:19ZRhabdomyosarcoma of the uterus in an adult patient with osteopetrosis: a case report10.1186/s13256-021-03172-y1752-1947https://doaj.org/article/a02fb4f9b6ec4eefa9824c8b0a68c3fb2021-11-01T00:00:00Zhttps://doi.org/10.1186/s13256-021-03172-yhttps://doaj.org/toc/1752-1947Abstract Background Uterine sarcoma accounts for 3–7% of uterine malignant neoplasms. It is more aggressive than epithelial neoplasms, and patients have a poor prognosis. Rhabdomyosarcoma is classified as a heterologous uterine sarcoma. It is the most common soft tissue malignancy in children while rare in adults. In young patients, the majority of genital tract rhabdomyosarcomas occur in vagina; however, the most common site of gynecologic rhabdomyosarcoma is cervix followed by uterine corpus, in adults. Uterine corpus rhabdomyosarcoma is rare in adults. Diagnosis of pure rhabdomyosarcoma in uterus involves widespread and perfect sampling as well as precise histopathological evaluation to uncover any epithelial component. Case presentation Here we report a case of pure rhabdomyosarcoma of uterine corpus in a 60-year-old Iranian postmenopausal female who had osteopetrosis, presenting with 8-month heavy vaginal bleeding and a protruding cervical mass. She is alive on 18-month follow-up after treatment. Conclusions Rhabdomyosarcoma of uterine corpus is rare in adults. Diagnosis of pure rhabdomyosarcoma in uterus involves widespread and perfect sampling as well as precise histopathological evaluation to uncover any epithelial component. Treatment options in adult gynecological rhabdomyosarcoma are based on studies in younger patients, and more studies may help us choose the best approach for improving outcome.Soheila AminimoghaddamAli RahbariRoghayeh PouraliBMCarticleRhabdomyosarcomaUterusSarcomaMedicineRENJournal of Medical Case Reports, Vol 15, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Rhabdomyosarcoma Uterus Sarcoma Medicine R
spellingShingle	Rhabdomyosarcoma Uterus Sarcoma Medicine R Soheila Aminimoghaddam Ali Rahbari Roghayeh Pourali Rhabdomyosarcoma of the uterus in an adult patient with osteopetrosis: a case report
description	Abstract Background Uterine sarcoma accounts for 3–7% of uterine malignant neoplasms. It is more aggressive than epithelial neoplasms, and patients have a poor prognosis. Rhabdomyosarcoma is classified as a heterologous uterine sarcoma. It is the most common soft tissue malignancy in children while rare in adults. In young patients, the majority of genital tract rhabdomyosarcomas occur in vagina; however, the most common site of gynecologic rhabdomyosarcoma is cervix followed by uterine corpus, in adults. Uterine corpus rhabdomyosarcoma is rare in adults. Diagnosis of pure rhabdomyosarcoma in uterus involves widespread and perfect sampling as well as precise histopathological evaluation to uncover any epithelial component. Case presentation Here we report a case of pure rhabdomyosarcoma of uterine corpus in a 60-year-old Iranian postmenopausal female who had osteopetrosis, presenting with 8-month heavy vaginal bleeding and a protruding cervical mass. She is alive on 18-month follow-up after treatment. Conclusions Rhabdomyosarcoma of uterine corpus is rare in adults. Diagnosis of pure rhabdomyosarcoma in uterus involves widespread and perfect sampling as well as precise histopathological evaluation to uncover any epithelial component. Treatment options in adult gynecological rhabdomyosarcoma are based on studies in younger patients, and more studies may help us choose the best approach for improving outcome.
format	article
author	Soheila Aminimoghaddam Ali Rahbari Roghayeh Pourali
author_facet	Soheila Aminimoghaddam Ali Rahbari Roghayeh Pourali
author_sort	Soheila Aminimoghaddam
title	Rhabdomyosarcoma of the uterus in an adult patient with osteopetrosis: a case report
title_short	Rhabdomyosarcoma of the uterus in an adult patient with osteopetrosis: a case report
title_full	Rhabdomyosarcoma of the uterus in an adult patient with osteopetrosis: a case report
title_fullStr	Rhabdomyosarcoma of the uterus in an adult patient with osteopetrosis: a case report
title_full_unstemmed	Rhabdomyosarcoma of the uterus in an adult patient with osteopetrosis: a case report
title_sort	rhabdomyosarcoma of the uterus in an adult patient with osteopetrosis: a case report
publisher	BMC
publishDate	2021
url	https://doaj.org/article/a02fb4f9b6ec4eefa9824c8b0a68c3fb
work_keys_str_mv	AT soheilaaminimoghaddam rhabdomyosarcomaoftheuterusinanadultpatientwithosteopetrosisacasereport AT alirahbari rhabdomyosarcomaoftheuterusinanadultpatientwithosteopetrosisacasereport AT roghayehpourali rhabdomyosarcomaoftheuterusinanadultpatientwithosteopetrosisacasereport
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Rhabdomyosarcoma of the uterus in an adult patient with osteopetrosis: a case report

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