Dimensionality reduction by UMAP to visualize physical and genetic interactions

Dimensionality reduction is often used to visualize expression profiling data in order to find relationships among cells. Here, the authors use Uniform Manifold Approximation and Projection (UMAP) on published expression data of gene deletions of S. cerevisiae to find novel protein interactions.

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Autores principales:	Michael W. Dorrity, Lauren M. Saunders, Christine Queitsch, Stanley Fields, Cole Trapnell
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a0311ead30404d9aa682e166ed1e7d83
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spelling	oai:doaj.org-article:a0311ead30404d9aa682e166ed1e7d832021-12-02T14:40:29ZDimensionality reduction by UMAP to visualize physical and genetic interactions10.1038/s41467-020-15351-42041-1723https://doaj.org/article/a0311ead30404d9aa682e166ed1e7d832020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15351-4https://doaj.org/toc/2041-1723Dimensionality reduction is often used to visualize expression profiling data in order to find relationships among cells. Here, the authors use Uniform Manifold Approximation and Projection (UMAP) on published expression data of gene deletions of S. cerevisiae to find novel protein interactions.Michael W. DorrityLauren M. SaundersChristine QueitschStanley FieldsCole TrapnellNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-6 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Michael W. Dorrity Lauren M. Saunders Christine Queitsch Stanley Fields Cole Trapnell Dimensionality reduction by UMAP to visualize physical and genetic interactions
description	Dimensionality reduction is often used to visualize expression profiling data in order to find relationships among cells. Here, the authors use Uniform Manifold Approximation and Projection (UMAP) on published expression data of gene deletions of S. cerevisiae to find novel protein interactions.
format	article
author	Michael W. Dorrity Lauren M. Saunders Christine Queitsch Stanley Fields Cole Trapnell
author_facet	Michael W. Dorrity Lauren M. Saunders Christine Queitsch Stanley Fields Cole Trapnell
author_sort	Michael W. Dorrity
title	Dimensionality reduction by UMAP to visualize physical and genetic interactions
title_short	Dimensionality reduction by UMAP to visualize physical and genetic interactions
title_full	Dimensionality reduction by UMAP to visualize physical and genetic interactions
title_fullStr	Dimensionality reduction by UMAP to visualize physical and genetic interactions
title_full_unstemmed	Dimensionality reduction by UMAP to visualize physical and genetic interactions
title_sort	dimensionality reduction by umap to visualize physical and genetic interactions
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/a0311ead30404d9aa682e166ed1e7d83
work_keys_str_mv	AT michaelwdorrity dimensionalityreductionbyumaptovisualizephysicalandgeneticinteractions AT laurenmsaunders dimensionalityreductionbyumaptovisualizephysicalandgeneticinteractions AT christinequeitsch dimensionalityreductionbyumaptovisualizephysicalandgeneticinteractions AT stanleyfields dimensionalityreductionbyumaptovisualizephysicalandgeneticinteractions AT coletrapnell dimensionalityreductionbyumaptovisualizephysicalandgeneticinteractions
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Dimensionality reduction by UMAP to visualize physical and genetic interactions

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