The spatial RNA integrity number assay for in situ evaluation of transcriptome quality

The spatial RNA integrity number assay for in situ evaluation of transcriptome quality

Kvastad et al. develop the spatial RNA Integrity Number (sRIN) assay that evaluates the RNA integrity at cellular resolution. This method improves the resolution of a similar method called the RNA Integrity Number (RIN), demonstrating spatial variation in the quality of RNA samples.

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Autores principales: Linda Kvastad, Konstantin Carlberg, Ludvig Larsson, Eva Gracia Villacampa, Alexander Stuckey, Linnea Stenbeck, Annelie Mollbrink, Margherita Zamboni, Jens Peter Magnusson, Elisa Basmaci, Alia Shamikh, Gabriela Prochazka, Anna-Lena Schaupp, Åke Borg, Lars Fugger, Monica Nistér, Joakim Lundeberg
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/a033c3e188a14f6b83ea0282f3e8e5a2
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spelling oai:doaj.org-article:a033c3e188a14f6b83ea0282f3e8e5a22021-12-02T15:13:13ZThe spatial RNA integrity number assay for in situ evaluation of transcriptome quality10.1038/s42003-020-01573-12399-3642https://doaj.org/article/a033c3e188a14f6b83ea0282f3e8e5a22021-01-01T00:00:00Zhttps://doi.org/10.1038/s42003-020-01573-1https://doaj.org/toc/2399-3642Kvastad et al. develop the spatial RNA Integrity Number (sRIN) assay that evaluates the RNA integrity at cellular resolution. This method improves the resolution of a similar method called the RNA Integrity Number (RIN), demonstrating spatial variation in the quality of RNA samples.Linda KvastadKonstantin CarlbergLudvig LarssonEva Gracia VillacampaAlexander StuckeyLinnea StenbeckAnnelie MollbrinkMargherita ZamboniJens Peter MagnussonElisa BasmaciAlia ShamikhGabriela ProchazkaAnna-Lena SchauppÅke BorgLars FuggerMonica NistérJoakim LundebergNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-8 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Linda Kvastad
Konstantin Carlberg
Ludvig Larsson
Eva Gracia Villacampa
Alexander Stuckey
Linnea Stenbeck
Annelie Mollbrink
Margherita Zamboni
Jens Peter Magnusson
Elisa Basmaci
Alia Shamikh
Gabriela Prochazka
Anna-Lena Schaupp
Åke Borg
Lars Fugger
Monica Nistér
Joakim Lundeberg
The spatial RNA integrity number assay for in situ evaluation of transcriptome quality
description Kvastad et al. develop the spatial RNA Integrity Number (sRIN) assay that evaluates the RNA integrity at cellular resolution. This method improves the resolution of a similar method called the RNA Integrity Number (RIN), demonstrating spatial variation in the quality of RNA samples.
format article
author Linda Kvastad
Konstantin Carlberg
Ludvig Larsson
Eva Gracia Villacampa
Alexander Stuckey
Linnea Stenbeck
Annelie Mollbrink
Margherita Zamboni
Jens Peter Magnusson
Elisa Basmaci
Alia Shamikh
Gabriela Prochazka
Anna-Lena Schaupp
Åke Borg
Lars Fugger
Monica Nistér
Joakim Lundeberg
author_facet Linda Kvastad
Konstantin Carlberg
Ludvig Larsson
Eva Gracia Villacampa
Alexander Stuckey
Linnea Stenbeck
Annelie Mollbrink
Margherita Zamboni
Jens Peter Magnusson
Elisa Basmaci
Alia Shamikh
Gabriela Prochazka
Anna-Lena Schaupp
Åke Borg
Lars Fugger
Monica Nistér
Joakim Lundeberg
author_sort Linda Kvastad
title The spatial RNA integrity number assay for in situ evaluation of transcriptome quality
title_short The spatial RNA integrity number assay for in situ evaluation of transcriptome quality
title_full The spatial RNA integrity number assay for in situ evaluation of transcriptome quality
title_fullStr The spatial RNA integrity number assay for in situ evaluation of transcriptome quality
title_full_unstemmed The spatial RNA integrity number assay for in situ evaluation of transcriptome quality
title_sort spatial rna integrity number assay for in situ evaluation of transcriptome quality
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/a033c3e188a14f6b83ea0282f3e8e5a2
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