Intracranial Castleman disease: Illustrative case and literature review
Introduction: Intracranial Castleman disease (CD) is an extremely rare and poorly-understood lymphoproliferative disorder with only a handful of case reports in the literature. CD most commonly presents with focal extracranial lymph node enlargement.Case report:A 30-year-old female presented with he...
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| Autores principales: | , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/a0398877bc51457498b2efd3b3a0f2d9 |
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| Sumario: | Introduction: Intracranial Castleman disease (CD) is an extremely rare and poorly-understood lymphoproliferative disorder with only a handful of case reports in the literature. CD most commonly presents with focal extracranial lymph node enlargement.Case report:A 30-year-old female presented with headaches and generalized tonic-clonic seizure. Imaging demonstrated an enhancing extra-axial dural-based mass in the right parietal convexity. The patient underwent gross total resection via a right parietal craniotomy and was discharged without complications. At 6-month follow-up, the patient remained neurologically intact with resolved preoperative symptomatology. Conclusions: The authors present a rare case of intracranial CD of the dura and elucidate specific histopathological characteristics. This case illustrates the importance of resection of the enhancing dural component in addition to the utility of a follow-up whole body PET-CT. Imaging characteristics of CD mimic an en plaque meningioma, and neurosurgical and hematologic management strategies of CD are unique. |
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