Short duration of focal onset awareness and impaired awareness seizure are characteristic features of epilepsy in elderly patients

Ayataka Fujimoto,1 Tohru Okanishi,1 Yosuke Masuda,1 Keishiro Sato,1 Mitsuyo Nishimura,1 Shimpei Baba,1 Shinji Itamura,1 Yoichiro Homma,2 Hideo Enoki1 1Comprehensive Epilepsy Center, Seirei Hamamatsu General Hospital, Hamamatsu, Shizuoka, Japan; 2Department of General Internal Medicine, Seirei Hamama...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Fujimoto A, Okanishi T, Masuda Y, Sato K, Nishimura M, Baba S, Itamura S, Homma Y, Enoki H
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	epilepsy in elderly less than 1-minute seizure consciousness level cognitive impairment concomitant symptoms Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/a042d5f8bdc344479c974700e97a2263
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:a042d5f8bdc344479c974700e97a2263
record_format	dspace
spelling	oai:doaj.org-article:a042d5f8bdc344479c974700e97a22632021-12-02T06:00:05ZShort duration of focal onset awareness and impaired awareness seizure are characteristic features of epilepsy in elderly patients1178-2021https://doaj.org/article/a042d5f8bdc344479c974700e97a22632018-10-01T00:00:00Zhttps://www.dovepress.com/short-duration-of-focal-onset-awareness-and-impaired-awareness-seizure-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Ayataka Fujimoto,1 Tohru Okanishi,1 Yosuke Masuda,1 Keishiro Sato,1 Mitsuyo Nishimura,1 Shimpei Baba,1 Shinji Itamura,1 Yoichiro Homma,2 Hideo Enoki1 1Comprehensive Epilepsy Center, Seirei Hamamatsu General Hospital, Hamamatsu, Shizuoka, Japan; 2Department of General Internal Medicine, Seirei Hamamatsu General Hospital, Hamamatsu, Shizuoka, Japan Purpose: Diagnosing epilepsy in the elderly population can be difficult due to mimicking symptoms. Furthermore, epileptic symptoms can also be masked by various symptoms. We hypothesized that elderly patients with epilepsy exhibit specific clinical features among the various symptoms.Patients and methods: From 2009 to 2017, 177 patients who were older than 65 years were referred to our epilepsy center. Out of this group, the onset of symptoms occurred after reaching the age of 50 years in 152 of the patients, who were additionally being treated at our clinic. We divided their symptoms in accordance with their consciousness levels, which were defined as follows: full wakefulness level I, impaired awareness level II, and loss of consciousness level III. We also classified the duration of the symptoms as <10 seconds, ≥10 seconds but <1 minute, ≥1 minute but <5 minutes, ≥5 minutes but <10 minutes, ≥10 minutes but <1 hour, and ≥1 hour.Results: Among the 152 patients analyzed (mean age 72.9 years, standard deviation 6.71, range 65–92), 84 patients had epilepsy (epilepsy group) while 68 did not exhibit epilepsy (nonepilepsy group). For the consciousness levels, there were more level I patients in the nonepilepsy vs epilepsy group (P<0.028), with symptom duration lasting <1 minute (sensitivity 0.857, specificity 1) in the epilepsy group. In contrast, there were more level II patients in the epilepsy vs the nonepilepsy group (P=0.015), with the duration of symptoms lasting <1 minute (sensitivity 0.8125, specificity 0.930) in the epilepsy group. For the level III consciousness, convulsions were more commonly seen in the epilepsy group (P=0.044).Conclusion: Symptoms that last <1 minute with awareness and impaired awareness might be epileptic in the elderly population. Keywords: epilepsy in elderly, <1-minute seizure, consciousness level, cognitive impairment, concomitant symptomsFujimoto AOkanishi TMasuda YSato KNishimura MBaba SItamura SHomma YEnoki HDove Medical Pressarticleepilepsy in elderlyless than 1-minute seizureconsciousness levelcognitive impairmentconcomitant symptomsNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 14, Pp 2879-2887 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	epilepsy in elderly less than 1-minute seizure consciousness level cognitive impairment concomitant symptoms Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	epilepsy in elderly less than 1-minute seizure consciousness level cognitive impairment concomitant symptoms Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Fujimoto A Okanishi T Masuda Y Sato K Nishimura M Baba S Itamura S Homma Y Enoki H Short duration of focal onset awareness and impaired awareness seizure are characteristic features of epilepsy in elderly patients
description	Ayataka Fujimoto,1 Tohru Okanishi,1 Yosuke Masuda,1 Keishiro Sato,1 Mitsuyo Nishimura,1 Shimpei Baba,1 Shinji Itamura,1 Yoichiro Homma,2 Hideo Enoki1 1Comprehensive Epilepsy Center, Seirei Hamamatsu General Hospital, Hamamatsu, Shizuoka, Japan; 2Department of General Internal Medicine, Seirei Hamamatsu General Hospital, Hamamatsu, Shizuoka, Japan Purpose: Diagnosing epilepsy in the elderly population can be difficult due to mimicking symptoms. Furthermore, epileptic symptoms can also be masked by various symptoms. We hypothesized that elderly patients with epilepsy exhibit specific clinical features among the various symptoms.Patients and methods: From 2009 to 2017, 177 patients who were older than 65 years were referred to our epilepsy center. Out of this group, the onset of symptoms occurred after reaching the age of 50 years in 152 of the patients, who were additionally being treated at our clinic. We divided their symptoms in accordance with their consciousness levels, which were defined as follows: full wakefulness level I, impaired awareness level II, and loss of consciousness level III. We also classified the duration of the symptoms as <10 seconds, ≥10 seconds but <1 minute, ≥1 minute but <5 minutes, ≥5 minutes but <10 minutes, ≥10 minutes but <1 hour, and ≥1 hour.Results: Among the 152 patients analyzed (mean age 72.9 years, standard deviation 6.71, range 65–92), 84 patients had epilepsy (epilepsy group) while 68 did not exhibit epilepsy (nonepilepsy group). For the consciousness levels, there were more level I patients in the nonepilepsy vs epilepsy group (P<0.028), with symptom duration lasting <1 minute (sensitivity 0.857, specificity 1) in the epilepsy group. In contrast, there were more level II patients in the epilepsy vs the nonepilepsy group (P=0.015), with the duration of symptoms lasting <1 minute (sensitivity 0.8125, specificity 0.930) in the epilepsy group. For the level III consciousness, convulsions were more commonly seen in the epilepsy group (P=0.044).Conclusion: Symptoms that last <1 minute with awareness and impaired awareness might be epileptic in the elderly population. Keywords: epilepsy in elderly, <1-minute seizure, consciousness level, cognitive impairment, concomitant symptoms
format	article
author	Fujimoto A Okanishi T Masuda Y Sato K Nishimura M Baba S Itamura S Homma Y Enoki H
author_facet	Fujimoto A Okanishi T Masuda Y Sato K Nishimura M Baba S Itamura S Homma Y Enoki H
author_sort	Fujimoto A
title	Short duration of focal onset awareness and impaired awareness seizure are characteristic features of epilepsy in elderly patients
title_short	Short duration of focal onset awareness and impaired awareness seizure are characteristic features of epilepsy in elderly patients
title_full	Short duration of focal onset awareness and impaired awareness seizure are characteristic features of epilepsy in elderly patients
title_fullStr	Short duration of focal onset awareness and impaired awareness seizure are characteristic features of epilepsy in elderly patients
title_full_unstemmed	Short duration of focal onset awareness and impaired awareness seizure are characteristic features of epilepsy in elderly patients
title_sort	short duration of focal onset awareness and impaired awareness seizure are characteristic features of epilepsy in elderly patients
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/a042d5f8bdc344479c974700e97a2263
work_keys_str_mv	AT fujimotoa shortdurationoffocalonsetawarenessandimpairedawarenessseizurearecharacteristicfeaturesofepilepsyinelderlypatients AT okanishit shortdurationoffocalonsetawarenessandimpairedawarenessseizurearecharacteristicfeaturesofepilepsyinelderlypatients AT masuday shortdurationoffocalonsetawarenessandimpairedawarenessseizurearecharacteristicfeaturesofepilepsyinelderlypatients AT satok shortdurationoffocalonsetawarenessandimpairedawarenessseizurearecharacteristicfeaturesofepilepsyinelderlypatients AT nishimuram shortdurationoffocalonsetawarenessandimpairedawarenessseizurearecharacteristicfeaturesofepilepsyinelderlypatients AT babas shortdurationoffocalonsetawarenessandimpairedawarenessseizurearecharacteristicfeaturesofepilepsyinelderlypatients AT itamuras shortdurationoffocalonsetawarenessandimpairedawarenessseizurearecharacteristicfeaturesofepilepsyinelderlypatients AT hommay shortdurationoffocalonsetawarenessandimpairedawarenessseizurearecharacteristicfeaturesofepilepsyinelderlypatients AT enokih shortdurationoffocalonsetawarenessandimpairedawarenessseizurearecharacteristicfeaturesofepilepsyinelderlypatients
_version_	1718400124708716544

Short duration of focal onset awareness and impaired awareness seizure are characteristic features of epilepsy in elderly patients

Ejemplares similares