Influence of critical hypotension on the development of postoperative hepatic failure

The article is devoted to the study of influence of critical hypotension on the development of postoperative hepatic failure. The results of treatment of 54 patients who had. anatomical and advanced anatomical resections of a liver were analyzed. Also the causes that lead to the postoperative hepati...

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Autores principales:	N. G. Kornilov, S. P. Chikoteev, M. V. Prokopiev, S. A. Lepekhova, N. I. Prokopieva, L. V. Gaskina, N. A. Kleimenova
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2013
Materias:	hepatic failure resection of liver hypotention Science Q
Acceso en línea:	https://doaj.org/article/a0493af67843452082c27f2593e5092d
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spelling	oai:doaj.org-article:a0493af67843452082c27f2593e5092d2021-11-23T06:14:25ZInfluence of critical hypotension on the development of postoperative hepatic failure2541-94202587-9596https://doaj.org/article/a0493af67843452082c27f2593e5092d2013-02-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1399https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The article is devoted to the study of influence of critical hypotension on the development of postoperative hepatic failure. The results of treatment of 54 patients who had. anatomical and advanced anatomical resections of a liver were analyzed. Also the causes that lead to the postoperative hepatic failure such as volume of intraoperative blood loss, duration of intraoperative hypotension were analyzed. As the result of the analysis of obtained data on the influence of studied parameters (volume of blood loss, duration. of vascular isolation and presence of intraoperative hypotension) on the development of hepatic failure in postoperative period we supposed that the most unfavorable prognostic sign of its appearance is an episode of critical decrease of arterial pressure during the operation. Thus even at massive blood loss hepatic failure doesn't always appear, whereas critical intraoperative hypotension causes its development. Taking into consideration data on the state of central hemodynamics at the performing of anatomic resections of liver we determined main approaches to the infusion-transfusion therapy during excluding of liver from blood circulation for the prophylactics of its reperfusion injuries. It was established that prophylactics and timely correction of critical intraoperative hypotenstion that is the main factor of development of postoperative hepatic failure should be considered as the key moments of intraoperative protection of hepatocytes.N. G. KornilovS. P. ChikoteevM. V. ProkopievS. A. LepekhovaN. I. ProkopievaL. V. GaskinaN. A. KleimenovaScientific Сentre for Family Health and Human Reproduction Problemsarticlehepatic failureresection of liverhypotentionScienceQRUActa Biomedica Scientifica, Vol 0, Iss 1, Pp 29-33 (2013)
institution	DOAJ
collection	DOAJ
language	RU
topic	hepatic failure resection of liver hypotention Science Q
spellingShingle	hepatic failure resection of liver hypotention Science Q N. G. Kornilov S. P. Chikoteev M. V. Prokopiev S. A. Lepekhova N. I. Prokopieva L. V. Gaskina N. A. Kleimenova Influence of critical hypotension on the development of postoperative hepatic failure
description	The article is devoted to the study of influence of critical hypotension on the development of postoperative hepatic failure. The results of treatment of 54 patients who had. anatomical and advanced anatomical resections of a liver were analyzed. Also the causes that lead to the postoperative hepatic failure such as volume of intraoperative blood loss, duration of intraoperative hypotension were analyzed. As the result of the analysis of obtained data on the influence of studied parameters (volume of blood loss, duration. of vascular isolation and presence of intraoperative hypotension) on the development of hepatic failure in postoperative period we supposed that the most unfavorable prognostic sign of its appearance is an episode of critical decrease of arterial pressure during the operation. Thus even at massive blood loss hepatic failure doesn't always appear, whereas critical intraoperative hypotension causes its development. Taking into consideration data on the state of central hemodynamics at the performing of anatomic resections of liver we determined main approaches to the infusion-transfusion therapy during excluding of liver from blood circulation for the prophylactics of its reperfusion injuries. It was established that prophylactics and timely correction of critical intraoperative hypotenstion that is the main factor of development of postoperative hepatic failure should be considered as the key moments of intraoperative protection of hepatocytes.
format	article
author	N. G. Kornilov S. P. Chikoteev M. V. Prokopiev S. A. Lepekhova N. I. Prokopieva L. V. Gaskina N. A. Kleimenova
author_facet	N. G. Kornilov S. P. Chikoteev M. V. Prokopiev S. A. Lepekhova N. I. Prokopieva L. V. Gaskina N. A. Kleimenova
author_sort	N. G. Kornilov
title	Influence of critical hypotension on the development of postoperative hepatic failure
title_short	Influence of critical hypotension on the development of postoperative hepatic failure
title_full	Influence of critical hypotension on the development of postoperative hepatic failure
title_fullStr	Influence of critical hypotension on the development of postoperative hepatic failure
title_full_unstemmed	Influence of critical hypotension on the development of postoperative hepatic failure
title_sort	influence of critical hypotension on the development of postoperative hepatic failure
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2013
url	https://doaj.org/article/a0493af67843452082c27f2593e5092d
work_keys_str_mv	AT ngkornilov influenceofcriticalhypotensiononthedevelopmentofpostoperativehepaticfailure AT spchikoteev influenceofcriticalhypotensiononthedevelopmentofpostoperativehepaticfailure AT mvprokopiev influenceofcriticalhypotensiononthedevelopmentofpostoperativehepaticfailure AT salepekhova influenceofcriticalhypotensiononthedevelopmentofpostoperativehepaticfailure AT niprokopieva influenceofcriticalhypotensiononthedevelopmentofpostoperativehepaticfailure AT lvgaskina influenceofcriticalhypotensiononthedevelopmentofpostoperativehepaticfailure AT nakleimenova influenceofcriticalhypotensiononthedevelopmentofpostoperativehepaticfailure
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Influence of critical hypotension on the development of postoperative hepatic failure

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