Versatile live-cell activity analysis platform for characterization of neuronal dynamics at single-cell and network level

Current methods of neuronal network imaging cannot be used for continuous, long-term functional recordings. Here, the authors present a dual-mode high-density microelectrode array, which can simultaneously record in full-frame and high-signal-to-noise modes for label-free electrophysiological measur...

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Autores principales: Xinyue Yuan, Manuel Schröter, Marie Engelene J. Obien, Michele Fiscella, Wei Gong, Tetsuhiro Kikuchi, Aoi Odawara, Shuhei Noji, Ikuro Suzuki, Jun Takahashi, Andreas Hierlemann, Urs Frey
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/a0577c2ed2304ba1ab8ed0c9e23fe0c6
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Sumario:Current methods of neuronal network imaging cannot be used for continuous, long-term functional recordings. Here, the authors present a dual-mode high-density microelectrode array, which can simultaneously record in full-frame and high-signal-to-noise modes for label-free electrophysiological measurements.