Versatile live-cell activity analysis platform for characterization of neuronal dynamics at single-cell and network level

Current methods of neuronal network imaging cannot be used for continuous, long-term functional recordings. Here, the authors present a dual-mode high-density microelectrode array, which can simultaneously record in full-frame and high-signal-to-noise modes for label-free electrophysiological measur...

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Autores principales:	Xinyue Yuan, Manuel Schröter, Marie Engelene J. Obien, Michele Fiscella, Wei Gong, Tetsuhiro Kikuchi, Aoi Odawara, Shuhei Noji, Ikuro Suzuki, Jun Takahashi, Andreas Hierlemann, Urs Frey
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a0577c2ed2304ba1ab8ed0c9e23fe0c6
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spelling	oai:doaj.org-article:a0577c2ed2304ba1ab8ed0c9e23fe0c62021-12-02T15:14:48ZVersatile live-cell activity analysis platform for characterization of neuronal dynamics at single-cell and network level10.1038/s41467-020-18620-42041-1723https://doaj.org/article/a0577c2ed2304ba1ab8ed0c9e23fe0c62020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18620-4https://doaj.org/toc/2041-1723Current methods of neuronal network imaging cannot be used for continuous, long-term functional recordings. Here, the authors present a dual-mode high-density microelectrode array, which can simultaneously record in full-frame and high-signal-to-noise modes for label-free electrophysiological measurements.Xinyue YuanManuel SchröterMarie Engelene J. ObienMichele FiscellaWei GongTetsuhiro KikuchiAoi OdawaraShuhei NojiIkuro SuzukiJun TakahashiAndreas HierlemannUrs FreyNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xinyue Yuan Manuel Schröter Marie Engelene J. Obien Michele Fiscella Wei Gong Tetsuhiro Kikuchi Aoi Odawara Shuhei Noji Ikuro Suzuki Jun Takahashi Andreas Hierlemann Urs Frey Versatile live-cell activity analysis platform for characterization of neuronal dynamics at single-cell and network level
description	Current methods of neuronal network imaging cannot be used for continuous, long-term functional recordings. Here, the authors present a dual-mode high-density microelectrode array, which can simultaneously record in full-frame and high-signal-to-noise modes for label-free electrophysiological measurements.
format	article
author	Xinyue Yuan Manuel Schröter Marie Engelene J. Obien Michele Fiscella Wei Gong Tetsuhiro Kikuchi Aoi Odawara Shuhei Noji Ikuro Suzuki Jun Takahashi Andreas Hierlemann Urs Frey
author_facet	Xinyue Yuan Manuel Schröter Marie Engelene J. Obien Michele Fiscella Wei Gong Tetsuhiro Kikuchi Aoi Odawara Shuhei Noji Ikuro Suzuki Jun Takahashi Andreas Hierlemann Urs Frey
author_sort	Xinyue Yuan
title	Versatile live-cell activity analysis platform for characterization of neuronal dynamics at single-cell and network level
title_short	Versatile live-cell activity analysis platform for characterization of neuronal dynamics at single-cell and network level
title_full	Versatile live-cell activity analysis platform for characterization of neuronal dynamics at single-cell and network level
title_fullStr	Versatile live-cell activity analysis platform for characterization of neuronal dynamics at single-cell and network level
title_full_unstemmed	Versatile live-cell activity analysis platform for characterization of neuronal dynamics at single-cell and network level
title_sort	versatile live-cell activity analysis platform for characterization of neuronal dynamics at single-cell and network level
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/a0577c2ed2304ba1ab8ed0c9e23fe0c6
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Versatile live-cell activity analysis platform for characterization of neuronal dynamics at single-cell and network level

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