Should Pneumococcal Vaccines Eliminate Nasopharyngeal Colonization?

ABSTRACT Streptococcus pneumoniae remains an important human pathogen. For more than 100 years, there have been vaccine efforts to prevent pneumococcal infection. The pneumococcal conjugate vaccines have significantly reduced invasive disease. However, these vaccines have changed pneumococcal ecolo...

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Autores principales:	Larry S. McDaniel, Edwin Swiatlo
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2016
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/a069c49f0a1241f6a37902ad06692e1e
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spelling	oai:doaj.org-article:a069c49f0a1241f6a37902ad06692e1e2021-11-15T15:50:17ZShould Pneumococcal Vaccines Eliminate Nasopharyngeal Colonization?10.1128/mBio.00545-162150-7511https://doaj.org/article/a069c49f0a1241f6a37902ad06692e1e2016-07-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00545-16https://doaj.org/toc/2150-7511ABSTRACT Streptococcus pneumoniae remains an important human pathogen. For more than 100 years, there have been vaccine efforts to prevent pneumococcal infection. The pneumococcal conjugate vaccines have significantly reduced invasive disease. However, these vaccines have changed pneumococcal ecology within the human nasopharynx. We suggest that elimination of the pneumococcus from the human nasopharynx can have consequences that should be considered as the next generation of pneumococcal vaccines is developed.Larry S. McDanielEdwin SwiatloAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 7, Iss 3 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Larry S. McDaniel Edwin Swiatlo Should Pneumococcal Vaccines Eliminate Nasopharyngeal Colonization?
description	ABSTRACT Streptococcus pneumoniae remains an important human pathogen. For more than 100 years, there have been vaccine efforts to prevent pneumococcal infection. The pneumococcal conjugate vaccines have significantly reduced invasive disease. However, these vaccines have changed pneumococcal ecology within the human nasopharynx. We suggest that elimination of the pneumococcus from the human nasopharynx can have consequences that should be considered as the next generation of pneumococcal vaccines is developed.
format	article
author	Larry S. McDaniel Edwin Swiatlo
author_facet	Larry S. McDaniel Edwin Swiatlo
author_sort	Larry S. McDaniel
title	Should Pneumococcal Vaccines Eliminate Nasopharyngeal Colonization?
title_short	Should Pneumococcal Vaccines Eliminate Nasopharyngeal Colonization?
title_full	Should Pneumococcal Vaccines Eliminate Nasopharyngeal Colonization?
title_fullStr	Should Pneumococcal Vaccines Eliminate Nasopharyngeal Colonization?
title_full_unstemmed	Should Pneumococcal Vaccines Eliminate Nasopharyngeal Colonization?
title_sort	should pneumococcal vaccines eliminate nasopharyngeal colonization?
publisher	American Society for Microbiology
publishDate	2016
url	https://doaj.org/article/a069c49f0a1241f6a37902ad06692e1e
work_keys_str_mv	AT larrysmcdaniel shouldpneumococcalvaccineseliminatenasopharyngealcolonization AT edwinswiatlo shouldpneumococcalvaccineseliminatenasopharyngealcolonization
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Should Pneumococcal Vaccines Eliminate Nasopharyngeal Colonization?

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