The Fatty Acid Species and Quantity Consumed by the Breastfed Infant Are Important for Growth and Development

The fatty acids (FAs) of human milk (HM) are the building blocks of the HM lipidome, contributing to infant health and development; however, this has not been comprehensively characterised with respect to infant intake. Eighteen Western Australian mother–infant dyads provided monthly longitudinal HM...

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Autores principales:	Alexandra D. George, Melvin C. L. Gay, Mary E. Wlodek, Kevin Murray, Donna T. Geddes
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	infant nutrition breastfeeding lipidomics Nutrition. Foods and food supply TX341-641
Acceso en línea:	https://doaj.org/article/a074eb60336a45fda605211e84702ef2
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spelling	oai:doaj.org-article:a074eb60336a45fda605211e84702ef22021-11-25T18:37:25ZThe Fatty Acid Species and Quantity Consumed by the Breastfed Infant Are Important for Growth and Development10.3390/nu131141832072-6643https://doaj.org/article/a074eb60336a45fda605211e84702ef22021-11-01T00:00:00Zhttps://www.mdpi.com/2072-6643/13/11/4183https://doaj.org/toc/2072-6643The fatty acids (FAs) of human milk (HM) are the building blocks of the HM lipidome, contributing to infant health and development; however, this has not been comprehensively characterised with respect to infant intake. Eighteen Western Australian mother–infant dyads provided monthly longitudinal HM samples during six months of exclusive breastfeeding. Monthly anthropometric measurements, health data and basic maternal food frequency data were also collected. At three months, infant 24 h milk intake and total lipid intake were measured. The FA profile was analysed using gas chromatography–mass spectrometry. Linear regression and Pearson’s correlation were used to identify associations between HM FA composition, HM FA intake, maternal characteristics and infant growth and developmental outcomes. Mean infant intake of total lipids was 29.7 ± 9.4 g/day. HM FA composition exhibited wide variation between dyads and throughout lactation. Infant intake of a number of FAs, including C15:0, C18:1, C18:2 and C20:3, was positively related to infant growth (all <i>p</i> < 0.001). There were no relationships detected between C22:5 and C20:5 and infant head circumference. Infant total lipid intake and the infant intake of many FAs play essential roles in infant growth and development. This study highlights the important relationships of many HM FAs not previously described, including C15:0 and C18:2 species. Infant outcomes should be considered in the context of intake in future HM studies.Alexandra D. GeorgeMelvin C. L. GayMary E. WlodekKevin MurrayDonna T. GeddesMDPI AGarticleinfant nutritionbreastfeedinglipidomicsNutrition. Foods and food supplyTX341-641ENNutrients, Vol 13, Iss 4183, p 4183 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	infant nutrition breastfeeding lipidomics Nutrition. Foods and food supply TX341-641
spellingShingle	infant nutrition breastfeeding lipidomics Nutrition. Foods and food supply TX341-641 Alexandra D. George Melvin C. L. Gay Mary E. Wlodek Kevin Murray Donna T. Geddes The Fatty Acid Species and Quantity Consumed by the Breastfed Infant Are Important for Growth and Development
description	The fatty acids (FAs) of human milk (HM) are the building blocks of the HM lipidome, contributing to infant health and development; however, this has not been comprehensively characterised with respect to infant intake. Eighteen Western Australian mother–infant dyads provided monthly longitudinal HM samples during six months of exclusive breastfeeding. Monthly anthropometric measurements, health data and basic maternal food frequency data were also collected. At three months, infant 24 h milk intake and total lipid intake were measured. The FA profile was analysed using gas chromatography–mass spectrometry. Linear regression and Pearson’s correlation were used to identify associations between HM FA composition, HM FA intake, maternal characteristics and infant growth and developmental outcomes. Mean infant intake of total lipids was 29.7 ± 9.4 g/day. HM FA composition exhibited wide variation between dyads and throughout lactation. Infant intake of a number of FAs, including C15:0, C18:1, C18:2 and C20:3, was positively related to infant growth (all <i>p</i> < 0.001). There were no relationships detected between C22:5 and C20:5 and infant head circumference. Infant total lipid intake and the infant intake of many FAs play essential roles in infant growth and development. This study highlights the important relationships of many HM FAs not previously described, including C15:0 and C18:2 species. Infant outcomes should be considered in the context of intake in future HM studies.
format	article
author	Alexandra D. George Melvin C. L. Gay Mary E. Wlodek Kevin Murray Donna T. Geddes
author_facet	Alexandra D. George Melvin C. L. Gay Mary E. Wlodek Kevin Murray Donna T. Geddes
author_sort	Alexandra D. George
title	The Fatty Acid Species and Quantity Consumed by the Breastfed Infant Are Important for Growth and Development
title_short	The Fatty Acid Species and Quantity Consumed by the Breastfed Infant Are Important for Growth and Development
title_full	The Fatty Acid Species and Quantity Consumed by the Breastfed Infant Are Important for Growth and Development
title_fullStr	The Fatty Acid Species and Quantity Consumed by the Breastfed Infant Are Important for Growth and Development
title_full_unstemmed	The Fatty Acid Species and Quantity Consumed by the Breastfed Infant Are Important for Growth and Development
title_sort	fatty acid species and quantity consumed by the breastfed infant are important for growth and development
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/a074eb60336a45fda605211e84702ef2
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The Fatty Acid Species and Quantity Consumed by the Breastfed Infant Are Important for Growth and Development

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