Axon degeneration induces glial responses through Draper-TRAF4-JNK signalling
The engulfment receptor Draper is known to promote glial activation and phagocytosis of debris upon axonal injury. Luet al. identify TNF receptor associated factor 4 (TRAF4) as a binding partner of Draper, and map out the signalling cascade leading to reactive gliosis in Drosophila.
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| Autores principales: | , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2017
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/a0803d1cf18d4b59932815bc571bcf90 |
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