Investigation of the prevalence of Cognitive Impairment and its risk factors within the elderly population in Shanghai, China

Abstract To investigate the prevalence of cognitive impairment and its risk factors among Chinese elders aged over 80 years, a community-based, cross-sectional study was conducted from May to June 2016 in Shanghai, China. Cognitive function was measured by using Mini-Mental Status Examination. Multi...

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Autores principales:	Longbing Ren, Yongtao Zheng, Lezhou Wu, Yijun Gu, Yusheng He, Bo Jiang, Jie Zhang, Lijuan Zhang, Jue Li
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a08404181fae4a668be22997cb6465ba
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spelling	oai:doaj.org-article:a08404181fae4a668be22997cb6465ba2021-12-02T11:40:54ZInvestigation of the prevalence of Cognitive Impairment and its risk factors within the elderly population in Shanghai, China10.1038/s41598-018-21983-w2045-2322https://doaj.org/article/a08404181fae4a668be22997cb6465ba2018-02-01T00:00:00Zhttps://doi.org/10.1038/s41598-018-21983-whttps://doaj.org/toc/2045-2322Abstract To investigate the prevalence of cognitive impairment and its risk factors among Chinese elders aged over 80 years, a community-based, cross-sectional study was conducted from May to June 2016 in Shanghai, China. Cognitive function was measured by using Mini-Mental Status Examination. Multiple logistic regression assessed associations between risk factors and cognitive impairment. Of 480 participants, 30% were diagnosed with cognitive impairment. Women [adjusted odds ratio (AOR): 1.71, 95% confidence interval (CI): 1.03–2.83], solitary life (AOR: 3.15, 1.89–5.26), monthly income less than 2000 Chinese yuan (AOR: 3.47, 1.18–10.23) were significantly associated with increased risk of cognitive impairment, compared with men, non-solitary life, and monthly income greater than 4000 Chinese yuan, respectively. Overweight (AOR: 0.59, 0.36–0.97), being physically active at least 60 minutes per day (AOR: 0.59, 0.35–0.95), antihypertensive drugs users (AOR: 0.45, 0.28–0.72), and lipid lowering drugs users (AOR: 0.21, 0.06–0.76) significantly lowered the risk of cognitive impairment, compared with normal weight, inadequate outdoor activity, and non-medication users, respectively. Accordingly, this study found that women, solitary life, lower income was associated with increased risk of cognitive impairment, while overweight, being physically active, and antihypertensive and lipid lowering drugs usage might lower the risk.Longbing RenYongtao ZhengLezhou WuYijun GuYusheng HeBo JiangJie ZhangLijuan ZhangJue LiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Longbing Ren Yongtao Zheng Lezhou Wu Yijun Gu Yusheng He Bo Jiang Jie Zhang Lijuan Zhang Jue Li Investigation of the prevalence of Cognitive Impairment and its risk factors within the elderly population in Shanghai, China
description	Abstract To investigate the prevalence of cognitive impairment and its risk factors among Chinese elders aged over 80 years, a community-based, cross-sectional study was conducted from May to June 2016 in Shanghai, China. Cognitive function was measured by using Mini-Mental Status Examination. Multiple logistic regression assessed associations between risk factors and cognitive impairment. Of 480 participants, 30% were diagnosed with cognitive impairment. Women [adjusted odds ratio (AOR): 1.71, 95% confidence interval (CI): 1.03–2.83], solitary life (AOR: 3.15, 1.89–5.26), monthly income less than 2000 Chinese yuan (AOR: 3.47, 1.18–10.23) were significantly associated with increased risk of cognitive impairment, compared with men, non-solitary life, and monthly income greater than 4000 Chinese yuan, respectively. Overweight (AOR: 0.59, 0.36–0.97), being physically active at least 60 minutes per day (AOR: 0.59, 0.35–0.95), antihypertensive drugs users (AOR: 0.45, 0.28–0.72), and lipid lowering drugs users (AOR: 0.21, 0.06–0.76) significantly lowered the risk of cognitive impairment, compared with normal weight, inadequate outdoor activity, and non-medication users, respectively. Accordingly, this study found that women, solitary life, lower income was associated with increased risk of cognitive impairment, while overweight, being physically active, and antihypertensive and lipid lowering drugs usage might lower the risk.
format	article
author	Longbing Ren Yongtao Zheng Lezhou Wu Yijun Gu Yusheng He Bo Jiang Jie Zhang Lijuan Zhang Jue Li
author_facet	Longbing Ren Yongtao Zheng Lezhou Wu Yijun Gu Yusheng He Bo Jiang Jie Zhang Lijuan Zhang Jue Li
author_sort	Longbing Ren
title	Investigation of the prevalence of Cognitive Impairment and its risk factors within the elderly population in Shanghai, China
title_short	Investigation of the prevalence of Cognitive Impairment and its risk factors within the elderly population in Shanghai, China
title_full	Investigation of the prevalence of Cognitive Impairment and its risk factors within the elderly population in Shanghai, China
title_fullStr	Investigation of the prevalence of Cognitive Impairment and its risk factors within the elderly population in Shanghai, China
title_full_unstemmed	Investigation of the prevalence of Cognitive Impairment and its risk factors within the elderly population in Shanghai, China
title_sort	investigation of the prevalence of cognitive impairment and its risk factors within the elderly population in shanghai, china
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/a08404181fae4a668be22997cb6465ba
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Investigation of the prevalence of Cognitive Impairment and its risk factors within the elderly population in Shanghai, China

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