A chromosome-scale assembly of the sorghum genome using nanopore sequencing and optical mapping

A chromosome-scale assembly of the sorghum genome using nanopore sequencing and optical mapping

Assembly of large, repeat-rich eukaryotic genomes remains challenging. Here, the authors use BioNano Genomics DLS optical mapping and single-molecule nanopore sequencing to generate a chromosome-scale assembly of a new Sorghum bicolor accession and identify variation compared to the publicly availab...

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Bibliographic Details
Main Authors: Stéphane Deschamps, Yun Zhang, Victor Llaca, Liang Ye, Abhijit Sanyal, Matthew King, Gregory May, Haining Lin
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Science
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Online Access:https://doaj.org/article/a094b1e394dd4d97aefd9a454c9da938
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Summary:Assembly of large, repeat-rich eukaryotic genomes remains challenging. Here, the authors use BioNano Genomics DLS optical mapping and single-molecule nanopore sequencing to generate a chromosome-scale assembly of a new Sorghum bicolor accession and identify variation compared to the publicly available S. bicolor genome.

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