A chromosome-scale assembly of the sorghum genome using nanopore sequencing and optical mapping

Assembly of large, repeat-rich eukaryotic genomes remains challenging. Here, the authors use BioNano Genomics DLS optical mapping and single-molecule nanopore sequencing to generate a chromosome-scale assembly of a new Sorghum bicolor accession and identify variation compared to the publicly availab...

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Autores principales: Stéphane Deschamps, Yun Zhang, Victor Llaca, Liang Ye, Abhijit Sanyal, Matthew King, Gregory May, Haining Lin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/a094b1e394dd4d97aefd9a454c9da938
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spelling oai:doaj.org-article:a094b1e394dd4d97aefd9a454c9da9382021-12-02T15:34:37ZA chromosome-scale assembly of the sorghum genome using nanopore sequencing and optical mapping10.1038/s41467-018-07271-12041-1723https://doaj.org/article/a094b1e394dd4d97aefd9a454c9da9382018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07271-1https://doaj.org/toc/2041-1723Assembly of large, repeat-rich eukaryotic genomes remains challenging. Here, the authors use BioNano Genomics DLS optical mapping and single-molecule nanopore sequencing to generate a chromosome-scale assembly of a new Sorghum bicolor accession and identify variation compared to the publicly available S. bicolor genome.Stéphane DeschampsYun ZhangVictor LlacaLiang YeAbhijit SanyalMatthew KingGregory MayHaining LinNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Stéphane Deschamps
Yun Zhang
Victor Llaca
Liang Ye
Abhijit Sanyal
Matthew King
Gregory May
Haining Lin
A chromosome-scale assembly of the sorghum genome using nanopore sequencing and optical mapping
description Assembly of large, repeat-rich eukaryotic genomes remains challenging. Here, the authors use BioNano Genomics DLS optical mapping and single-molecule nanopore sequencing to generate a chromosome-scale assembly of a new Sorghum bicolor accession and identify variation compared to the publicly available S. bicolor genome.
format article
author Stéphane Deschamps
Yun Zhang
Victor Llaca
Liang Ye
Abhijit Sanyal
Matthew King
Gregory May
Haining Lin
author_facet Stéphane Deschamps
Yun Zhang
Victor Llaca
Liang Ye
Abhijit Sanyal
Matthew King
Gregory May
Haining Lin
author_sort Stéphane Deschamps
title A chromosome-scale assembly of the sorghum genome using nanopore sequencing and optical mapping
title_short A chromosome-scale assembly of the sorghum genome using nanopore sequencing and optical mapping
title_full A chromosome-scale assembly of the sorghum genome using nanopore sequencing and optical mapping
title_fullStr A chromosome-scale assembly of the sorghum genome using nanopore sequencing and optical mapping
title_full_unstemmed A chromosome-scale assembly of the sorghum genome using nanopore sequencing and optical mapping
title_sort chromosome-scale assembly of the sorghum genome using nanopore sequencing and optical mapping
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/a094b1e394dd4d97aefd9a454c9da938
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