Viral Bcl2s’ transmembrane domain interact with host Bcl2 proteins to control cellular apoptosis

Viral analogs of B-cell lymphoma 2 (Bcl2), known as vBcl2s, control apoptosis by interacting with host pro- and anti-apoptotic members of the Bcl2 family. Here, García-Murria et al. report on transmembrane domains (TMDs) in the C-terminal hydrophobic region of herpes- and poxviral vBcl2s, which medi...

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Bibliographic Details
Main Authors: Maria Jesús García-Murria, Gerard Duart, Brayan Grau, Elisabet Diaz-Beneitez, Dolores Rodríguez, Ismael Mingarro, Luis Martínez-Gil
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/a095ff7f2cb74e3786be3ecd772374a0
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