Eliminating the capsule-like layer to promote glucose uptake for hyaluronan production by engineered Corynebacterium glutamicum

Bioproduction of hyaluronan needs increases in yield and greater diversity of the molecular weights. Here, the author increases hyaluronan production and diversifies the molecular weights through engineering the hyaluronan biosynthesis pathway and disruption of Corynebacterium glutamicum encapsulati...

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Autores principales: Yang Wang, Litao Hu, Hao Huang, Hao Wang, Tianmeng Zhang, Jian Chen, Guocheng Du, Zhen Kang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/a09a0e7632894f51be0f5f47907650db
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spelling oai:doaj.org-article:a09a0e7632894f51be0f5f47907650db2021-12-02T17:40:27ZEliminating the capsule-like layer to promote glucose uptake for hyaluronan production by engineered Corynebacterium glutamicum10.1038/s41467-020-16962-72041-1723https://doaj.org/article/a09a0e7632894f51be0f5f47907650db2020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16962-7https://doaj.org/toc/2041-1723Bioproduction of hyaluronan needs increases in yield and greater diversity of the molecular weights. Here, the author increases hyaluronan production and diversifies the molecular weights through engineering the hyaluronan biosynthesis pathway and disruption of Corynebacterium glutamicum encapsulation caused by secreted hyaluronan.Yang WangLitao HuHao HuangHao WangTianmeng ZhangJian ChenGuocheng DuZhen KangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yang Wang
Litao Hu
Hao Huang
Hao Wang
Tianmeng Zhang
Jian Chen
Guocheng Du
Zhen Kang
Eliminating the capsule-like layer to promote glucose uptake for hyaluronan production by engineered Corynebacterium glutamicum
description Bioproduction of hyaluronan needs increases in yield and greater diversity of the molecular weights. Here, the author increases hyaluronan production and diversifies the molecular weights through engineering the hyaluronan biosynthesis pathway and disruption of Corynebacterium glutamicum encapsulation caused by secreted hyaluronan.
format article
author Yang Wang
Litao Hu
Hao Huang
Hao Wang
Tianmeng Zhang
Jian Chen
Guocheng Du
Zhen Kang
author_facet Yang Wang
Litao Hu
Hao Huang
Hao Wang
Tianmeng Zhang
Jian Chen
Guocheng Du
Zhen Kang
author_sort Yang Wang
title Eliminating the capsule-like layer to promote glucose uptake for hyaluronan production by engineered Corynebacterium glutamicum
title_short Eliminating the capsule-like layer to promote glucose uptake for hyaluronan production by engineered Corynebacterium glutamicum
title_full Eliminating the capsule-like layer to promote glucose uptake for hyaluronan production by engineered Corynebacterium glutamicum
title_fullStr Eliminating the capsule-like layer to promote glucose uptake for hyaluronan production by engineered Corynebacterium glutamicum
title_full_unstemmed Eliminating the capsule-like layer to promote glucose uptake for hyaluronan production by engineered Corynebacterium glutamicum
title_sort eliminating the capsule-like layer to promote glucose uptake for hyaluronan production by engineered corynebacterium glutamicum
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/a09a0e7632894f51be0f5f47907650db
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