β-arrestin mediates communication between plasma membrane and intracellular GPCRs to regulate signaling
DeNies et al. identify a new mechanism of intracellular GPCR signalling. Using CXC chemokine receptor 4 (CXCR4) as a model, they show that upon stimulation with receptor agonists that not only plasma membrane-localized receptors, but also intracellular CXCR4 molecules are post-translationally modifi...
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Autores principales: | Maxwell S. DeNies, Alan V. Smrcka, Santiago Schnell, Allen P. Liu |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/a0a094837ce448838dbe265fd50519a0 |
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