β-arrestin mediates communication between plasma membrane and intracellular GPCRs to regulate signaling

DeNies et al. identify a new mechanism of intracellular GPCR signalling. Using CXC chemokine receptor 4 (CXCR4) as a model, they show that upon stimulation with receptor agonists that not only plasma membrane-localized receptors, but also intracellular CXCR4 molecules are post-translationally modifi...

Full description

Saved in:
Bibliographic Details
Main Authors: Maxwell S. DeNies, Alan V. Smrcka, Santiago Schnell, Allen P. Liu
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Online Access:https://doaj.org/article/a0a094837ce448838dbe265fd50519a0
Tags: Add Tag
No Tags, Be the first to tag this record!