β-arrestin mediates communication between plasma membrane and intracellular GPCRs to regulate signaling

DeNies et al. identify a new mechanism of intracellular GPCR signalling. Using CXC chemokine receptor 4 (CXCR4) as a model, they show that upon stimulation with receptor agonists that not only plasma membrane-localized receptors, but also intracellular CXCR4 molecules are post-translationally modifi...

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Auteurs principaux: Maxwell S. DeNies, Alan V. Smrcka, Santiago Schnell, Allen P. Liu
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/a0a094837ce448838dbe265fd50519a0
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