Collateral sensitivity constrains resistance evolution of the CTX-M-15 β-lactamase
Development of bacterial resistance to an antibiotic can lead to collateral sensitivity to another drug. Here, the authors study collateral sensitivity conferred by mutations in the horizontally acquired β-lactamase CTX-M-15, and identify antibiotic combinations that constrain the evolution of resis...
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Autores principales: | Carola E. H. Rosenkilde, Christian Munck, Andreas Porse, Marius Linkevicius, Dan I. Andersson, Morten O. A. Sommer |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/a0a1a4e12b5342fc952264aa461d8831 |
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