Drug-related problems in patients with benign prostatic hyperplasia: a cross sectional retrospective study.

Benign Prostatic Hyperplasia (BPH) patients are at risk of acquiring drug-related problems (DRPs), as it is present in the majority of aging men. To date, DRPs among BPH patients have not been well studied. We conducted this retrospective study in a tertiary hospital in Malaysia from January 2009 to...

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Autores principales:	Hasniza Zaman Huri, Chong Hui Xin, Che Zuraini Sulaiman
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2014
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a0a259ceab87401c9ef36beb9054e1cc
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spelling	oai:doaj.org-article:a0a259ceab87401c9ef36beb9054e1cc2021-11-18T08:35:44ZDrug-related problems in patients with benign prostatic hyperplasia: a cross sectional retrospective study.1932-620310.1371/journal.pone.0086215https://doaj.org/article/a0a259ceab87401c9ef36beb9054e1cc2014-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24475089/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203Benign Prostatic Hyperplasia (BPH) patients are at risk of acquiring drug-related problems (DRPs), as it is present in the majority of aging men. To date, DRPs among BPH patients have not been well studied. We conducted this retrospective study in a tertiary hospital in Malaysia from January 2009 to June 2012 with the aim of identifying the factors associated with DRPs among BPH patients. The Pharmaceutical Care Network Europe Classification Version (PCNE) 5.01 was used as a tool to classify DRPs. We enrolled 203 patients from 259 hospital admissions. A total of 390 DRPs were found and there was an average of 1.5±1.3 problems per hospitalization. 76.1% of hospital admissions included at least one DRP. The most common DRP categories encountered were drug choice problems (45.9%), drug interactions (24.9%), and dosing problems (13.3%). Factors such as advanced age (p = 0.005), a hospital stay of more than 6 days (p = 0.001), polydrug treatments (p<0.001), multiple comorbidities (p<0.001), and comorbid cardiovascular disease (p = 0.011), diabetes mellitus(p = 0.001), hypertension (p<0.001) and renal impairment (p = 0.011) were significantly associated with the occurrence of DRPs. These data indicated that the prevalence of DRPs is high among BPH patients. The identification of different subtypes of DRPs and the factors associated with DRPs may facilitate risk reduction for BPH patients.Hasniza Zaman HuriChong Hui XinChe Zuraini SulaimanPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 1, p e86215 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Hasniza Zaman Huri Chong Hui Xin Che Zuraini Sulaiman Drug-related problems in patients with benign prostatic hyperplasia: a cross sectional retrospective study.
description	Benign Prostatic Hyperplasia (BPH) patients are at risk of acquiring drug-related problems (DRPs), as it is present in the majority of aging men. To date, DRPs among BPH patients have not been well studied. We conducted this retrospective study in a tertiary hospital in Malaysia from January 2009 to June 2012 with the aim of identifying the factors associated with DRPs among BPH patients. The Pharmaceutical Care Network Europe Classification Version (PCNE) 5.01 was used as a tool to classify DRPs. We enrolled 203 patients from 259 hospital admissions. A total of 390 DRPs were found and there was an average of 1.5±1.3 problems per hospitalization. 76.1% of hospital admissions included at least one DRP. The most common DRP categories encountered were drug choice problems (45.9%), drug interactions (24.9%), and dosing problems (13.3%). Factors such as advanced age (p = 0.005), a hospital stay of more than 6 days (p = 0.001), polydrug treatments (p<0.001), multiple comorbidities (p<0.001), and comorbid cardiovascular disease (p = 0.011), diabetes mellitus(p = 0.001), hypertension (p<0.001) and renal impairment (p = 0.011) were significantly associated with the occurrence of DRPs. These data indicated that the prevalence of DRPs is high among BPH patients. The identification of different subtypes of DRPs and the factors associated with DRPs may facilitate risk reduction for BPH patients.
format	article
author	Hasniza Zaman Huri Chong Hui Xin Che Zuraini Sulaiman
author_facet	Hasniza Zaman Huri Chong Hui Xin Che Zuraini Sulaiman
author_sort	Hasniza Zaman Huri
title	Drug-related problems in patients with benign prostatic hyperplasia: a cross sectional retrospective study.
title_short	Drug-related problems in patients with benign prostatic hyperplasia: a cross sectional retrospective study.
title_full	Drug-related problems in patients with benign prostatic hyperplasia: a cross sectional retrospective study.
title_fullStr	Drug-related problems in patients with benign prostatic hyperplasia: a cross sectional retrospective study.
title_full_unstemmed	Drug-related problems in patients with benign prostatic hyperplasia: a cross sectional retrospective study.
title_sort	drug-related problems in patients with benign prostatic hyperplasia: a cross sectional retrospective study.
publisher	Public Library of Science (PLoS)
publishDate	2014
url	https://doaj.org/article/a0a259ceab87401c9ef36beb9054e1cc
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Drug-related problems in patients with benign prostatic hyperplasia: a cross sectional retrospective study.

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