Duplication and Functional Divergence of Branched-Chain Amino Acid Biosynthesis Genes in Aspergillus nidulans
Branched-chain amino acid (BCAA) biosynthesis is important for pathogenic fungi to successfully cause disease in human and plant hosts. The enzymes for their production are absent from humans and, therefore, provide potential antifungal targets.
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American Society for Microbiology
2021
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oai:doaj.org-article:a0a5b01e50b849a097c691780cf045c62021-11-03T21:15:03ZDuplication and Functional Divergence of Branched-Chain Amino Acid Biosynthesis Genes in Aspergillus nidulans2150-751110.1128/mBio.00768-21https://doaj.org/article/a0a5b01e50b849a097c691780cf045c62021-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00768-21https://doaj.org/toc/2150-7511 Branched-chain amino acid (BCAA) biosynthesis is important for pathogenic fungi to successfully cause disease in human and plant hosts. The enzymes for their production are absent from humans and, therefore, provide potential antifungal targets.Joel T. SteyerDamien J. DownesCameron C. HunterPierre A. MigeonRichard B. ToddAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 3 (2021) |
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DOAJ |
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DOAJ |
language |
EN |
topic |
Microbiology QR1-502 |
spellingShingle |
Microbiology QR1-502 Joel T. Steyer Damien J. Downes Cameron C. Hunter Pierre A. Migeon Richard B. Todd Duplication and Functional Divergence of Branched-Chain Amino Acid Biosynthesis Genes in Aspergillus nidulans |
description |
Branched-chain amino acid (BCAA) biosynthesis is important for pathogenic fungi to successfully cause disease in human and plant hosts. The enzymes for their production are absent from humans and, therefore, provide potential antifungal targets. |
format |
article |
author |
Joel T. Steyer Damien J. Downes Cameron C. Hunter Pierre A. Migeon Richard B. Todd |
author_facet |
Joel T. Steyer Damien J. Downes Cameron C. Hunter Pierre A. Migeon Richard B. Todd |
author_sort |
Joel T. Steyer |
title |
Duplication and Functional Divergence of Branched-Chain Amino Acid Biosynthesis Genes in Aspergillus nidulans |
title_short |
Duplication and Functional Divergence of Branched-Chain Amino Acid Biosynthesis Genes in Aspergillus nidulans |
title_full |
Duplication and Functional Divergence of Branched-Chain Amino Acid Biosynthesis Genes in Aspergillus nidulans |
title_fullStr |
Duplication and Functional Divergence of Branched-Chain Amino Acid Biosynthesis Genes in Aspergillus nidulans |
title_full_unstemmed |
Duplication and Functional Divergence of Branched-Chain Amino Acid Biosynthesis Genes in Aspergillus nidulans |
title_sort |
duplication and functional divergence of branched-chain amino acid biosynthesis genes in aspergillus nidulans |
publisher |
American Society for Microbiology |
publishDate |
2021 |
url |
https://doaj.org/article/a0a5b01e50b849a097c691780cf045c6 |
work_keys_str_mv |
AT joeltsteyer duplicationandfunctionaldivergenceofbranchedchainaminoacidbiosynthesisgenesinaspergillusnidulans AT damienjdownes duplicationandfunctionaldivergenceofbranchedchainaminoacidbiosynthesisgenesinaspergillusnidulans AT cameronchunter duplicationandfunctionaldivergenceofbranchedchainaminoacidbiosynthesisgenesinaspergillusnidulans AT pierreamigeon duplicationandfunctionaldivergenceofbranchedchainaminoacidbiosynthesisgenesinaspergillusnidulans AT richardbtodd duplicationandfunctionaldivergenceofbranchedchainaminoacidbiosynthesisgenesinaspergillusnidulans |
_version_ |
1718445411727835136 |