Duplication and Functional Divergence of Branched-Chain Amino Acid Biosynthesis Genes in Aspergillus nidulans

Branched-chain amino acid (BCAA) biosynthesis is important for pathogenic fungi to successfully cause disease in human and plant hosts. The enzymes for their production are absent from humans and, therefore, provide potential antifungal targets.

Guardado en:
Detalles Bibliográficos
Autores principales: Joel T. Steyer, Damien J. Downes, Cameron C. Hunter, Pierre A. Migeon, Richard B. Todd
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://doaj.org/article/a0a5b01e50b849a097c691780cf045c6
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:a0a5b01e50b849a097c691780cf045c6
record_format dspace
spelling oai:doaj.org-article:a0a5b01e50b849a097c691780cf045c62021-11-03T21:15:03ZDuplication and Functional Divergence of Branched-Chain Amino Acid Biosynthesis Genes in Aspergillus nidulans2150-751110.1128/mBio.00768-21https://doaj.org/article/a0a5b01e50b849a097c691780cf045c62021-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00768-21https://doaj.org/toc/2150-7511 Branched-chain amino acid (BCAA) biosynthesis is important for pathogenic fungi to successfully cause disease in human and plant hosts. The enzymes for their production are absent from humans and, therefore, provide potential antifungal targets.Joel T. SteyerDamien J. DownesCameron C. HunterPierre A. MigeonRichard B. ToddAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 3 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Joel T. Steyer
Damien J. Downes
Cameron C. Hunter
Pierre A. Migeon
Richard B. Todd
Duplication and Functional Divergence of Branched-Chain Amino Acid Biosynthesis Genes in Aspergillus nidulans
description Branched-chain amino acid (BCAA) biosynthesis is important for pathogenic fungi to successfully cause disease in human and plant hosts. The enzymes for their production are absent from humans and, therefore, provide potential antifungal targets.
format article
author Joel T. Steyer
Damien J. Downes
Cameron C. Hunter
Pierre A. Migeon
Richard B. Todd
author_facet Joel T. Steyer
Damien J. Downes
Cameron C. Hunter
Pierre A. Migeon
Richard B. Todd
author_sort Joel T. Steyer
title Duplication and Functional Divergence of Branched-Chain Amino Acid Biosynthesis Genes in Aspergillus nidulans
title_short Duplication and Functional Divergence of Branched-Chain Amino Acid Biosynthesis Genes in Aspergillus nidulans
title_full Duplication and Functional Divergence of Branched-Chain Amino Acid Biosynthesis Genes in Aspergillus nidulans
title_fullStr Duplication and Functional Divergence of Branched-Chain Amino Acid Biosynthesis Genes in Aspergillus nidulans
title_full_unstemmed Duplication and Functional Divergence of Branched-Chain Amino Acid Biosynthesis Genes in Aspergillus nidulans
title_sort duplication and functional divergence of branched-chain amino acid biosynthesis genes in aspergillus nidulans
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/a0a5b01e50b849a097c691780cf045c6
work_keys_str_mv AT joeltsteyer duplicationandfunctionaldivergenceofbranchedchainaminoacidbiosynthesisgenesinaspergillusnidulans
AT damienjdownes duplicationandfunctionaldivergenceofbranchedchainaminoacidbiosynthesisgenesinaspergillusnidulans
AT cameronchunter duplicationandfunctionaldivergenceofbranchedchainaminoacidbiosynthesisgenesinaspergillusnidulans
AT pierreamigeon duplicationandfunctionaldivergenceofbranchedchainaminoacidbiosynthesisgenesinaspergillusnidulans
AT richardbtodd duplicationandfunctionaldivergenceofbranchedchainaminoacidbiosynthesisgenesinaspergillusnidulans
_version_ 1718445411727835136