K-doped ZnO nanostructures: biosynthesis and parasiticidal application

In general, the growing resistance to traditional anti-leishmaniasis drugs and the ineffectiveness of appropriate treatment for leishmaniasis have prompted researchers to investigate the antiparasitic properties of plant-mediated synthesized nanomaterials and nanosystems. Potassium (K)-doped zinc ox...

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Autores principales: Yan Cao, Hajar Q. Alijani, Mehrdad Khatami, Fatemeh Bagheri-Baravati, Siavash Iravani, Fatemeh Sharifi
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Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/a0b164a9dfe64763a939c2975975eb7c
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spelling oai:doaj.org-article:a0b164a9dfe64763a939c2975975eb7c2021-11-20T05:06:35ZK-doped ZnO nanostructures: biosynthesis and parasiticidal application2238-785410.1016/j.jmrt.2021.10.137https://doaj.org/article/a0b164a9dfe64763a939c2975975eb7c2021-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2238785421012746https://doaj.org/toc/2238-7854In general, the growing resistance to traditional anti-leishmaniasis drugs and the ineffectiveness of appropriate treatment for leishmaniasis have prompted researchers to investigate the antiparasitic properties of plant-mediated synthesized nanomaterials and nanosystems. Potassium (K)-doped zinc oxide (ZnO) nanostructures with unique physicochemical properties can be employed as attractive candidate against this parasitic disease. In this study, K-doped zinc oxide (KdZ) nanoparticles (NPs) were synthesized using Artemisia annua extracts via an eco-friendly method with the advantages of simplicity, low cost, and up-scalability. A. annua extracts were deployed due to their antiparasitic effects. The synthesized NPs were characterized by X-ray powder diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), and transmission electron microscopy (TEM). The toxicity of these nanostructures was evaluated on Leishmania tropica and normal macrophage cells. As a result, the K-doped ZnO NPs could inhibit the L. tropica cells growth, in vitro.Yan CaoHajar Q. AlijaniMehrdad KhatamiFatemeh Bagheri-BaravatiSiavash IravaniFatemeh SharifiElsevierarticleK-doped ZnO nanoparticlesArtemisia annuaGreen synthesisLeishmania tropicaMining engineering. MetallurgyTN1-997ENJournal of Materials Research and Technology, Vol 15, Iss , Pp 5445-5451 (2021)
institution DOAJ
collection DOAJ
language EN
topic K-doped ZnO nanoparticles
Artemisia annua
Green synthesis
Leishmania tropica
Mining engineering. Metallurgy
TN1-997
spellingShingle K-doped ZnO nanoparticles
Artemisia annua
Green synthesis
Leishmania tropica
Mining engineering. Metallurgy
TN1-997
Yan Cao
Hajar Q. Alijani
Mehrdad Khatami
Fatemeh Bagheri-Baravati
Siavash Iravani
Fatemeh Sharifi
K-doped ZnO nanostructures: biosynthesis and parasiticidal application
description In general, the growing resistance to traditional anti-leishmaniasis drugs and the ineffectiveness of appropriate treatment for leishmaniasis have prompted researchers to investigate the antiparasitic properties of plant-mediated synthesized nanomaterials and nanosystems. Potassium (K)-doped zinc oxide (ZnO) nanostructures with unique physicochemical properties can be employed as attractive candidate against this parasitic disease. In this study, K-doped zinc oxide (KdZ) nanoparticles (NPs) were synthesized using Artemisia annua extracts via an eco-friendly method with the advantages of simplicity, low cost, and up-scalability. A. annua extracts were deployed due to their antiparasitic effects. The synthesized NPs were characterized by X-ray powder diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), and transmission electron microscopy (TEM). The toxicity of these nanostructures was evaluated on Leishmania tropica and normal macrophage cells. As a result, the K-doped ZnO NPs could inhibit the L. tropica cells growth, in vitro.
format article
author Yan Cao
Hajar Q. Alijani
Mehrdad Khatami
Fatemeh Bagheri-Baravati
Siavash Iravani
Fatemeh Sharifi
author_facet Yan Cao
Hajar Q. Alijani
Mehrdad Khatami
Fatemeh Bagheri-Baravati
Siavash Iravani
Fatemeh Sharifi
author_sort Yan Cao
title K-doped ZnO nanostructures: biosynthesis and parasiticidal application
title_short K-doped ZnO nanostructures: biosynthesis and parasiticidal application
title_full K-doped ZnO nanostructures: biosynthesis and parasiticidal application
title_fullStr K-doped ZnO nanostructures: biosynthesis and parasiticidal application
title_full_unstemmed K-doped ZnO nanostructures: biosynthesis and parasiticidal application
title_sort k-doped zno nanostructures: biosynthesis and parasiticidal application
publisher Elsevier
publishDate 2021
url https://doaj.org/article/a0b164a9dfe64763a939c2975975eb7c
work_keys_str_mv AT yancao kdopedznonanostructuresbiosynthesisandparasiticidalapplication
AT hajarqalijani kdopedznonanostructuresbiosynthesisandparasiticidalapplication
AT mehrdadkhatami kdopedznonanostructuresbiosynthesisandparasiticidalapplication
AT fatemehbagheribaravati kdopedznonanostructuresbiosynthesisandparasiticidalapplication
AT siavashiravani kdopedznonanostructuresbiosynthesisandparasiticidalapplication
AT fatemehsharifi kdopedznonanostructuresbiosynthesisandparasiticidalapplication
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