Synthesis of high-titer alka(e)nes in Yarrowia lipolytica is enabled by a discovered mechanism

Alka(e)nes with chain lengths in C5-C23 range are ideal fuel components. Here, the authors report that high-titer production of alak(e)nes in pathway engineered Yarrowia lipolytica, which is enabled by the finding that acyl-CoA is another substrate of fatty acid photodecarboxylase (FAP).

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Autores principales: Jingbo Li, Yongshuo Ma, Nian Liu, Bekir E. Eser, Zheng Guo, Peter Ruhdal Jensen, Gregory Stephanopoulos
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/a0b420a3083742b8b797a64e9b649e3a
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spelling oai:doaj.org-article:a0b420a3083742b8b797a64e9b649e3a2021-12-02T16:49:29ZSynthesis of high-titer alka(e)nes in Yarrowia lipolytica is enabled by a discovered mechanism10.1038/s41467-020-19995-02041-1723https://doaj.org/article/a0b420a3083742b8b797a64e9b649e3a2020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19995-0https://doaj.org/toc/2041-1723Alka(e)nes with chain lengths in C5-C23 range are ideal fuel components. Here, the authors report that high-titer production of alak(e)nes in pathway engineered Yarrowia lipolytica, which is enabled by the finding that acyl-CoA is another substrate of fatty acid photodecarboxylase (FAP).Jingbo LiYongshuo MaNian LiuBekir E. EserZheng GuoPeter Ruhdal JensenGregory StephanopoulosNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jingbo Li
Yongshuo Ma
Nian Liu
Bekir E. Eser
Zheng Guo
Peter Ruhdal Jensen
Gregory Stephanopoulos
Synthesis of high-titer alka(e)nes in Yarrowia lipolytica is enabled by a discovered mechanism
description Alka(e)nes with chain lengths in C5-C23 range are ideal fuel components. Here, the authors report that high-titer production of alak(e)nes in pathway engineered Yarrowia lipolytica, which is enabled by the finding that acyl-CoA is another substrate of fatty acid photodecarboxylase (FAP).
format article
author Jingbo Li
Yongshuo Ma
Nian Liu
Bekir E. Eser
Zheng Guo
Peter Ruhdal Jensen
Gregory Stephanopoulos
author_facet Jingbo Li
Yongshuo Ma
Nian Liu
Bekir E. Eser
Zheng Guo
Peter Ruhdal Jensen
Gregory Stephanopoulos
author_sort Jingbo Li
title Synthesis of high-titer alka(e)nes in Yarrowia lipolytica is enabled by a discovered mechanism
title_short Synthesis of high-titer alka(e)nes in Yarrowia lipolytica is enabled by a discovered mechanism
title_full Synthesis of high-titer alka(e)nes in Yarrowia lipolytica is enabled by a discovered mechanism
title_fullStr Synthesis of high-titer alka(e)nes in Yarrowia lipolytica is enabled by a discovered mechanism
title_full_unstemmed Synthesis of high-titer alka(e)nes in Yarrowia lipolytica is enabled by a discovered mechanism
title_sort synthesis of high-titer alka(e)nes in yarrowia lipolytica is enabled by a discovered mechanism
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/a0b420a3083742b8b797a64e9b649e3a
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