Microgravity induces inhibition of osteoblastic differentiation and mineralization through abrogating primary cilia

Abstract It is well documented that microgravity in space environment leads to bone loss in astronauts. These physiological changes have also been validated by human and animal studies and modeled in cell-based analogs. However, the underlying mechanisms are elusive. In the current study, we identif...

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Bibliographic Details
Main Authors: Wengui Shi, Yanfang Xie, Jinpeng He, Jian Zhou, Yuhai Gao, Wenjun Wei, Nan Ding, Huiping Ma, Cory J. Xian, Keming Chen, Jufang Wang
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/a0be59ecfd824f6e9e318cb14dc4d29a
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